Effects of non-invasive neurostimulation on craving: a meta-analysis

Jochem M. Jansen; Maarten W. J. Koeter; Dick J. Veltman; Wim van den Brink; Anna E. Goudriaan

doi:https://doi.org/10.1016/j.neubiorev.2013.07.009

Effects of non-invasive neurostimulation on craving: a meta-analysis

Jochem M. Jansen, Maarten W. J. Koeter, Dick J. Veltman, Wim van den Brink, Anna E. Goudriaan

Research output: Contribution to journal › Review article › Academic › peer-review

223 Citations (Scopus)

Abstract

This meta-analysis was conducted to evaluate the available evidence regarding the effects of non-invasive neurostimulation of the dorsolateral prefrontal cortex (DLPFC), on craving in substance dependence and craving for high palatable food. Non-invasive neurostimulation techniques were restricted to repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS). A total of 17 eligible studies were identified. Random effects analysis revealed a pooled standardized effect size (Hedge's g) of 0.476 (CI: 0.316-0.636), indicating a medium effect size favouring active non-invasive neurostimulation over sham stimulation in the reduction of craving (z=5.832, p <0.001). No significant differences were found between rTMS and tDCS, between the various substances of abuse and between substances of abuse and food, or between left and right DLPFC stimulation. In conclusion, this meta-analysis provides the first clear evidence that non-invasive neurostimulation of the DLPFC decreases craving levels in substance dependence

Original language	English
Pages (from-to)	2472-2480
Journal	Neuroscience and biobehavioral reviews
Volume	37
Issue number	10 Part 2
DOIs	https://doi.org/10.1016/j.neubiorev.2013.07.009
Publication status	Published - 2013

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https://doi.org/10.1016/j.neubiorev.2013.07.009

Cite this

@article{92d6db2e6a87454789fef053ea86554d,

title = "Effects of non-invasive neurostimulation on craving: a meta-analysis",

abstract = "This meta-analysis was conducted to evaluate the available evidence regarding the effects of non-invasive neurostimulation of the dorsolateral prefrontal cortex (DLPFC), on craving in substance dependence and craving for high palatable food. Non-invasive neurostimulation techniques were restricted to repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS). A total of 17 eligible studies were identified. Random effects analysis revealed a pooled standardized effect size (Hedge's g) of 0.476 (CI: 0.316-0.636), indicating a medium effect size favouring active non-invasive neurostimulation over sham stimulation in the reduction of craving (z=5.832, p <0.001). No significant differences were found between rTMS and tDCS, between the various substances of abuse and between substances of abuse and food, or between left and right DLPFC stimulation. In conclusion, this meta-analysis provides the first clear evidence that non-invasive neurostimulation of the DLPFC decreases craving levels in substance dependence",

author = "Jansen, {Jochem M.} and Koeter, {Maarten W. J.} and Veltman, {Dick J.} and {van den Brink}, Wim and Goudriaan, {Anna E.}",

year = "2013",

doi = "https://doi.org/10.1016/j.neubiorev.2013.07.009",

language = "English",

volume = "37",

pages = "2472--2480",

journal = "Neuroscience and biobehavioral reviews",

issn = "0149-7634",

publisher = "Elsevier Limited",

number = "10 Part 2",

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TY - JOUR

T1 - Effects of non-invasive neurostimulation on craving: a meta-analysis

AU - Jansen, Jochem M.

AU - Koeter, Maarten W. J.

AU - Veltman, Dick J.

AU - van den Brink, Wim

AU - Goudriaan, Anna E.

PY - 2013

Y1 - 2013

N2 - This meta-analysis was conducted to evaluate the available evidence regarding the effects of non-invasive neurostimulation of the dorsolateral prefrontal cortex (DLPFC), on craving in substance dependence and craving for high palatable food. Non-invasive neurostimulation techniques were restricted to repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS). A total of 17 eligible studies were identified. Random effects analysis revealed a pooled standardized effect size (Hedge's g) of 0.476 (CI: 0.316-0.636), indicating a medium effect size favouring active non-invasive neurostimulation over sham stimulation in the reduction of craving (z=5.832, p <0.001). No significant differences were found between rTMS and tDCS, between the various substances of abuse and between substances of abuse and food, or between left and right DLPFC stimulation. In conclusion, this meta-analysis provides the first clear evidence that non-invasive neurostimulation of the DLPFC decreases craving levels in substance dependence

AB - This meta-analysis was conducted to evaluate the available evidence regarding the effects of non-invasive neurostimulation of the dorsolateral prefrontal cortex (DLPFC), on craving in substance dependence and craving for high palatable food. Non-invasive neurostimulation techniques were restricted to repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS). A total of 17 eligible studies were identified. Random effects analysis revealed a pooled standardized effect size (Hedge's g) of 0.476 (CI: 0.316-0.636), indicating a medium effect size favouring active non-invasive neurostimulation over sham stimulation in the reduction of craving (z=5.832, p <0.001). No significant differences were found between rTMS and tDCS, between the various substances of abuse and between substances of abuse and food, or between left and right DLPFC stimulation. In conclusion, this meta-analysis provides the first clear evidence that non-invasive neurostimulation of the DLPFC decreases craving levels in substance dependence

U2 - https://doi.org/10.1016/j.neubiorev.2013.07.009

DO - https://doi.org/10.1016/j.neubiorev.2013.07.009

M3 - Review article

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SN - 0149-7634

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JO - Neuroscience and biobehavioral reviews

JF - Neuroscience and biobehavioral reviews

IS - 10 Part 2

ER -