A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

Cindy Zadikoff; Susan H. Fox; David F. Tang-Wai; Teri Thomsen; Rob M. A. de Bie; Pettarusup Wadia; Janis Miyasaki; Sarah Duff-Canning; Anthony E. Lang; Connie Marras

doi:https://doi.org/10.1002/mds.21837

A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

Cindy Zadikoff, Susan H. Fox, David F. Tang-Wai, Teri Thomsen, Rob M. A. de Bie, Pettarusup Wadia, Janis Miyasaki, Sarah Duff-Canning, Anthony E. Lang, Connie Marras

Research output: Contribution to journal › Article › Academic › peer-review

272 Citations (Scopus)

Abstract

Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7-30, 4.26) than with the MMSE(16-30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P <0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD. (C) 2007 Movement Disorder Society

Original language	English
Pages (from-to)	297-299
Journal	Movement disorders
Volume	23
Issue number	2
DOIs	https://doi.org/10.1002/mds.21837
Publication status	Published - 2008

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https://doi.org/10.1002/mds.21837

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title = "A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease",

abstract = "Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7-30, 4.26) than with the MMSE(16-30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P <0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD. (C) 2007 Movement Disorder Society",

author = "Cindy Zadikoff and Fox, {Susan H.} and Tang-Wai, {David F.} and Teri Thomsen and {de Bie}, {Rob M. A.} and Pettarusup Wadia and Janis Miyasaki and Sarah Duff-Canning and Lang, {Anthony E.} and Connie Marras",

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T1 - A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

AU - Zadikoff, Cindy

AU - Fox, Susan H.

AU - Tang-Wai, David F.

AU - Thomsen, Teri

AU - de Bie, Rob M. A.

AU - Wadia, Pettarusup

AU - Miyasaki, Janis

AU - Duff-Canning, Sarah

AU - Lang, Anthony E.

AU - Marras, Connie

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AB - Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7-30, 4.26) than with the MMSE(16-30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P <0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD. (C) 2007 Movement Disorder Society

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