A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment

Ellen Siebring-van Olst, Maxime Blijlevens, Renee X. de Menezes, Ida H. van der Meulen-Muileman, Egbert F. Smit, Victor W. van Beusechem

Research output: Contribution to JournalArticleAcademicpeer-review

39 Citations (Scopus)
Original languageEnglish
Pages (from-to)534-551
JournalMolecular Oncology
Volume11
Issue number5
DOIs
Publication statusPublished - May 2017

Keywords

  • NSCLC
  • RNA splice factor
  • RNAi screen
  • p53 pathway inhibitor
  • spliceosome

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