A guide to appropriately planning and conducting meta-analyses: part 2—effect size estimation, heterogeneity and analytic approaches

Kyle N. Kunze, Jeffrey Kay, Ayoosh Pareek, Jari Dahmen, Benedict U. Nwachukwu, Riley J. Williams, Jon Karlsson, Darren de SA

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Meta-analyses by definition are a subtype of systematic review intended to quantitatively assess the strength of evidence present on an intervention or treatment. Such analyses may use individual-level data or aggregate data to produce a point estimate of an effect, also known as the combined effect, and measure precision of the calculated estimate. The current article will review several important considerations during the analytic phase of a meta-analysis, including selection of effect estimators, heterogeneity and various sub-types of meta-analytic approaches.
Original languageEnglish
Pages (from-to)1629-1634
Number of pages6
JournalKnee surgery, sports traumatology, arthroscopy
Volume31
Issue number5
Early online date2023
DOIs
Publication statusPublished - May 2023

Keywords

  • Effect estimator
  • Fixed effects
  • Guidelines
  • Heterogeneity
  • Meta-analysis
  • Random effects
  • Statistic
  • Subtype

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