A guide to appropriately planning and conducting meta-analyses: part 2—effect size estimation, heterogeneity and analytic approaches

Kyle N. Kunze; Jeffrey Kay; Ayoosh Pareek; Jari Dahmen; Benedict U. Nwachukwu; Riley J. Williams; Jon Karlsson; Darren de SA

doi:https://doi.org/10.1007/s00167-023-07328-9

A guide to appropriately planning and conducting meta-analyses: part 2—effect size estimation, heterogeneity and analytic approaches

Kyle N. Kunze, Jeffrey Kay, Ayoosh Pareek, Jari Dahmen, Benedict U. Nwachukwu, Riley J. Williams, Jon Karlsson, Darren de SA

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Meta-analyses by definition are a subtype of systematic review intended to quantitatively assess the strength of evidence present on an intervention or treatment. Such analyses may use individual-level data or aggregate data to produce a point estimate of an effect, also known as the combined effect, and measure precision of the calculated estimate. The current article will review several important considerations during the analytic phase of a meta-analysis, including selection of effect estimators, heterogeneity and various sub-types of meta-analytic approaches.

Original language	English
Pages (from-to)	1629-1634
Number of pages	6
Journal	Knee surgery, sports traumatology, arthroscopy
Volume	31
Issue number	5
Early online date	2023
DOIs	https://doi.org/10.1007/s00167-023-07328-9
Publication status	Published - May 2023

Keywords

Effect estimator
Fixed effects
Guidelines
Heterogeneity
Meta-analysis
Random effects
Statistic
Subtype

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https://doi.org/10.1007/s00167-023-07328-9

Cite this

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abstract = "Meta-analyses by definition are a subtype of systematic review intended to quantitatively assess the strength of evidence present on an intervention or treatment. Such analyses may use individual-level data or aggregate data to produce a point estimate of an effect, also known as the combined effect, and measure precision of the calculated estimate. The current article will review several important considerations during the analytic phase of a meta-analysis, including selection of effect estimators, heterogeneity and various sub-types of meta-analytic approaches.",

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note = "Publisher Copyright: {\textcopyright} 2023, The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).",

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AU - Dahmen, Jari

AU - Nwachukwu, Benedict U.

AU - Williams, Riley J.

AU - Karlsson, Jon

AU - de SA, Darren

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KW - Guidelines

KW - Heterogeneity

KW - Meta-analysis

KW - Random effects

KW - Statistic

KW - Subtype

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SN - 0942-2056

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JO - Knee surgery, sports traumatology, arthroscopy

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A guide to appropriately planning and conducting meta-analyses: part 2—effect size estimation, heterogeneity and analytic approaches

Abstract

Keywords

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