A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria

M. Messmer; C. Florentz; H. Schwenzer; G.C. Scheper; M.S. van der Knaap; L. Marechal-Drouard; M. Sissler

doi:https://doi.org/10.1042/BJ20101902

A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria

M. Messmer, C. Florentz, H. Schwenzer, G.C. Scheper, M.S. van der Knaap, L. Marechal-Drouard, M. Sissler

Pediatric surgery (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Abstract

Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated with leukoencephalopathy. A Ser

Original language	English
Pages (from-to)	441-446
Journal	Biochemical journal
Volume	433
Issue number	3
DOIs	https://doi.org/10.1042/BJ20101902
Publication status	Published - 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

https://doi.org/10.1042/BJ20101902

Cite this

@article{b1442bddd5134bbdb66578879e980d23,

title = "A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria",

abstract = "Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated with leukoencephalopathy. A Ser",

author = "M. Messmer and C. Florentz and H. Schwenzer and G.C. Scheper and {van der Knaap}, M.S. and L. Marechal-Drouard and M. Sissler",

year = "2011",

doi = "https://doi.org/10.1042/BJ20101902",

language = "English",

volume = "433",

pages = "441--446",

journal = "Biochemical journal",

issn = "0264-6021",

publisher = "Portland Press Ltd.",

number = "3",

}

TY - JOUR

T1 - A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria

AU - Messmer, M.

AU - Florentz, C.

AU - Schwenzer, H.

AU - Scheper, G.C.

AU - van der Knaap, M.S.

AU - Marechal-Drouard, L.

AU - Sissler, M.

PY - 2011

Y1 - 2011

N2 - Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated with leukoencephalopathy. A Ser

AB - Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated with leukoencephalopathy. A Ser

U2 - https://doi.org/10.1042/BJ20101902

DO - https://doi.org/10.1042/BJ20101902

M3 - Article

C2 - 21121901

SN - 0264-6021

VL - 433

SP - 441

EP - 446

JO - Biochemical journal

JF - Biochemical journal

IS - 3

ER -