A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

E. Porcu; M. Medici; G. Pistis; C.B. Volpato; S.G. Wilson; A.R. Cappola; S.D. Bos; J. Deelen; M. den Heijer; R.M. Freathy; J. Lahti; C. Liu; L.M. Lopez; I.M. Nolte; J.R. O'Connell; T. Tanaka; S. Trompet; A. Arnold; S. Bandinelli; M. Beekman; S. Bohringer; S.J. Brown; B.M. Buckley; C. Camaschella; A.J. de Craen; G. Davies; M.C.H. de Visser; I. Ford; T. Forsen; T.M. Frayling; L. Fugazzola; M. Goegele; A.T. Hattersley; A.R. Hermus; A. Hofman; J.J. Houwing-Duistermaat; R.A. Jensen; E. Kajantie; M. Kloppenburg; E.M. Lim; C. Masciullo; S. Mariotti; C. Minelli; B.D. Mitchell; R. Nagaraja; R.T. Netea-Maier; A. Palotie; L. Persani; M.G. Piras; B.M. Psaty; K. Raikkonen; J. Richards; F. Rivadeneira; C. Sala; M.M. Sabra; N. Sattar; B.M. Shields; N. Soranzo; J. M. Starr; D.J. Stott; F.C. Sweep; G. Usala; M.M. van der Klauw; D. van Heemst; A. van Mullem; S.H. Vermeulen; W. Visser; J.P. Walsh; R.G. Westendorp; E. Widen; G. Zhai; F. Cucca; I. J. Deary; J.G. Eriksson; L. Ferrucci; C.S. Fox; J. Jukema; L.A. Kiemeney; P.P. Pramstaller; D. Schlessinger; A.R. Shuldiner; E.P. Slagboom; A. G. Uitterlinden; B. Vaidya; T.J. Visser; B.H. Wolffenbuttel; I. Meulenbelt; J.I. Rotter; T.D. Spector; A.A. Hicks; D. Toniolo; S. Sanna; R.P. Peeters; S. Naitza

doi:https://doi.org/10.1371/journal.pgen.1003266

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

E. Porcu, M. Medici, G. Pistis, C.B. Volpato, S.G. Wilson, A.R. Cappola, S.D. Bos, J. Deelen, M. den Heijer, R.M. Freathy, J. Lahti, C. Liu, L.M. Lopez, I.M. Nolte, J.R. O'Connell, T. Tanaka, S. Trompet, A. Arnold, S. Bandinelli, M. BeekmanS. Bohringer, S.J. Brown, B.M. Buckley, C. Camaschella, A.J. de Craen, G. Davies, M.C.H. de Visser, I. Ford, T. Forsen, T.M. Frayling, L. Fugazzola, M. Goegele, A.T. Hattersley, A.R. Hermus, A. Hofman, J.J. Houwing-Duistermaat, R.A. Jensen, E. Kajantie, M. Kloppenburg, E.M. Lim, C. Masciullo, S. Mariotti, C. Minelli, B.D. Mitchell, R. Nagaraja, R.T. Netea-Maier, A. Palotie, L. Persani, M.G. Piras, B.M. Psaty, K. Raikkonen, J. Richards, F. Rivadeneira, C. Sala, M.M. Sabra, N. Sattar, B.M. Shields, N. Soranzo, J. M. Starr, D.J. Stott, F.C. Sweep, G. Usala, M.M. van der Klauw, D. van Heemst, A. van Mullem, S.H. Vermeulen, W. Visser, J.P. Walsh, R.G. Westendorp, E. Widen, G. Zhai, F. Cucca, I. J. Deary, J.G. Eriksson, L. Ferrucci, C.S. Fox, J. Jukema, L.A. Kiemeney, P.P. Pramstaller, D. Schlessinger, A.R. Shuldiner, E.P. Slagboom, A. G. Uitterlinden, B. Vaidya, T.J. Visser, B.H. Wolffenbuttel, I. Meulenbelt, J.I. Rotter, T.D. Spector, A.A. Hicks, D. Toniolo, S. Sanna, R.P. Peeters, S. Naitza

Internal Medicine (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

177 Citations (Scopus)

Original language	Undefined/Unknown
Article number	e1003266
Journal	PLoS genetics
Volume	9
Issue number	2
DOIs	https://doi.org/10.1371/journal.pgen.1003266
Publication status	Published - 2013

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https://doi.org/10.1371/journal.pgen.1003266

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Porcu, E., Medici, M., Pistis, G., Volpato, C. B., Wilson, S. G., Cappola, A. R., Bos, S. D., Deelen, J., den Heijer, M., Freathy, R. M., Lahti, J., Liu, C., Lopez, L. M., Nolte, I. M., O'Connell, J. R., Tanaka, T., Trompet, S., Arnold, A., Bandinelli, S., ... Naitza, S. (2013). A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function. PLoS genetics, 9(2), Article e1003266. https://doi.org/10.1371/journal.pgen.1003266

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title = "A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function",

author = "E. Porcu and M. Medici and G. Pistis and C.B. Volpato and S.G. Wilson and A.R. Cappola and S.D. Bos and J. Deelen and {den Heijer}, M. and R.M. Freathy and J. Lahti and C. Liu and L.M. Lopez and I.M. Nolte and J.R. O'Connell and T. Tanaka and S. Trompet and A. Arnold and S. Bandinelli and M. Beekman and S. Bohringer and S.J. Brown and B.M. Buckley and C. Camaschella and {de Craen}, A.J. and G. Davies and {de Visser}, M.C.H. and I. Ford and T. Forsen and T.M. Frayling and L. Fugazzola and M. Goegele and A.T. Hattersley and A.R. Hermus and A. Hofman and J.J. Houwing-Duistermaat and R.A. Jensen and E. Kajantie and M. Kloppenburg and E.M. Lim and C. Masciullo and S. Mariotti and C. Minelli and B.D. Mitchell and R. Nagaraja and R.T. Netea-Maier and A. Palotie and L. Persani and M.G. Piras and B.M. Psaty and K. Raikkonen and J. Richards and F. Rivadeneira and C. Sala and M.M. Sabra and N. Sattar and B.M. Shields and N. Soranzo and Starr, {J. M.} and D.J. Stott and F.C. Sweep and G. Usala and {van der Klauw}, M.M. and {van Heemst}, D. and {van Mullem}, A. and S.H. Vermeulen and W. Visser and J.P. Walsh and R.G. Westendorp and E. Widen and G. Zhai and F. Cucca and Deary, {I. J.} and J.G. Eriksson and L. Ferrucci and C.S. Fox and J. Jukema and L.A. Kiemeney and P.P. Pramstaller and D. Schlessinger and A.R. Shuldiner and E.P. Slagboom and Uitterlinden, {A. G.} and B. Vaidya and T.J. Visser and B.H. Wolffenbuttel and I. Meulenbelt and J.I. Rotter and T.D. Spector and A.A. Hicks and D. Toniolo and S. Sanna and R.P. Peeters and S. Naitza",

year = "2013",

doi = "https://doi.org/10.1371/journal.pgen.1003266",

language = "Undefined/Unknown",

volume = "9",

journal = "PLoS genetics",

issn = "1553-7390",

publisher = "Public Library of Science",

number = "2",

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Porcu, E, Medici, M, Pistis, G, Volpato, CB, Wilson, SG, Cappola, AR, Bos, SD, Deelen, J, den Heijer, M, Freathy, RM, Lahti, J, Liu, C, Lopez, LM, Nolte, IM, O'Connell, JR, Tanaka, T, Trompet, S, Arnold, A, Bandinelli, S, Beekman, M, Bohringer, S, Brown, SJ, Buckley, BM, Camaschella, C, de Craen, AJ, Davies, G, de Visser, MCH, Ford, I, Forsen, T, Frayling, TM, Fugazzola, L, Goegele, M, Hattersley, AT, Hermus, AR, Hofman, A, Houwing-Duistermaat, JJ, Jensen, RA, Kajantie, E, Kloppenburg, M, Lim, EM, Masciullo, C, Mariotti, S, Minelli, C, Mitchell, BD, Nagaraja, R, Netea-Maier, RT, Palotie, A, Persani, L, Piras, MG, Psaty, BM, Raikkonen, K, Richards, J, Rivadeneira, F, Sala, C, Sabra, MM, Sattar, N, Shields, BM, Soranzo, N, Starr, JM, Stott, DJ, Sweep, FC, Usala, G, van der Klauw, MM, van Heemst, D, van Mullem, A, Vermeulen, SH, Visser, W, Walsh, JP, Westendorp, RG, Widen, E, Zhai, G, Cucca, F, Deary, IJ, Eriksson, JG, Ferrucci, L, Fox, CS, Jukema, J, Kiemeney, LA, Pramstaller, PP, Schlessinger, D, Shuldiner, AR, Slagboom, EP, Uitterlinden, AG, Vaidya, B, Visser, TJ, Wolffenbuttel, BH, Meulenbelt, I, Rotter, JI, Spector, TD, Hicks, AA, Toniolo, D, Sanna, S, Peeters, RP & Naitza, S 2013, 'A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function', PLoS genetics, vol. 9, no. 2, e1003266. https://doi.org/10.1371/journal.pgen.1003266

TY - JOUR

T1 - A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

AU - Porcu, E.

AU - Medici, M.

AU - Pistis, G.

AU - Volpato, C.B.

AU - Wilson, S.G.

AU - Cappola, A.R.

AU - Bos, S.D.

AU - Deelen, J.

AU - den Heijer, M.

AU - Freathy, R.M.

AU - Lahti, J.

AU - Liu, C.

AU - Lopez, L.M.

AU - Nolte, I.M.

AU - O'Connell, J.R.

AU - Tanaka, T.

AU - Trompet, S.

AU - Arnold, A.

AU - Bandinelli, S.

AU - Beekman, M.

AU - Bohringer, S.

AU - Brown, S.J.

AU - Buckley, B.M.

AU - Camaschella, C.

AU - de Craen, A.J.

AU - Davies, G.

AU - de Visser, M.C.H.

AU - Ford, I.

AU - Forsen, T.

AU - Frayling, T.M.

AU - Fugazzola, L.

AU - Goegele, M.

AU - Hattersley, A.T.

AU - Hermus, A.R.

AU - Hofman, A.

AU - Houwing-Duistermaat, J.J.

AU - Jensen, R.A.

AU - Kajantie, E.

AU - Kloppenburg, M.

AU - Lim, E.M.

AU - Masciullo, C.

AU - Mariotti, S.

AU - Minelli, C.

AU - Mitchell, B.D.

AU - Nagaraja, R.

AU - Netea-Maier, R.T.

AU - Palotie, A.

AU - Persani, L.

AU - Piras, M.G.

AU - Psaty, B.M.

AU - Raikkonen, K.

AU - Richards, J.

AU - Rivadeneira, F.

AU - Sala, C.

AU - Sabra, M.M.

AU - Sattar, N.

AU - Shields, B.M.

AU - Soranzo, N.

AU - Starr, J. M.

AU - Stott, D.J.

AU - Sweep, F.C.

AU - Usala, G.

AU - van der Klauw, M.M.

AU - van Heemst, D.

AU - van Mullem, A.

AU - Vermeulen, S.H.

AU - Visser, W.

AU - Walsh, J.P.

AU - Westendorp, R.G.

AU - Widen, E.

AU - Zhai, G.

AU - Cucca, F.

AU - Deary, I. J.

AU - Eriksson, J.G.

AU - Ferrucci, L.

AU - Fox, C.S.

AU - Jukema, J.

AU - Kiemeney, L.A.

AU - Pramstaller, P.P.

AU - Schlessinger, D.

AU - Shuldiner, A.R.

AU - Slagboom, E.P.

AU - Uitterlinden, A. G.

AU - Vaidya, B.

AU - Visser, T.J.

AU - Wolffenbuttel, B.H.

AU - Meulenbelt, I.

AU - Rotter, J.I.

AU - Spector, T.D.

AU - Hicks, A.A.

AU - Toniolo, D.

AU - Sanna, S.

AU - Peeters, R.P.

AU - Naitza, S.

PY - 2013

Y1 - 2013

U2 - https://doi.org/10.1371/journal.pgen.1003266

DO - https://doi.org/10.1371/journal.pgen.1003266

M3 - Article

C2 - 23408906

SN - 1553-7390

VL - 9

JO - PLoS genetics

JF - PLoS genetics

IS - 2

M1 - e1003266

ER -