TY - JOUR
T1 - A multimodal interdisciplinary rehabilitation programme (HAPPY) for patients undergoing allogeneic non-myeloablative haematopoietic stem cell transplantation
T2 - A feasibility study
AU - Lindman, Astrid
AU - Handberg, Charlotte
AU - Olesen, Gitte
AU - Duijts, Saskia
N1 - Funding Information: This work was supported by the Health Research Fund of Central Denmark Region, Denmark ; The Novo Nordic Foundation, Denmark [grant NNF17OC0029978 ] and [grant NNF19OC0059033 ]; Internal research funding at Aarhus University Hospital, Denmark ; The sponsors were not involved in study design, data collection, data analysis, interpretation of data, writing of the report or in writing the article. Publisher Copyright: © 2023
PY - 2023/8/1
Y1 - 2023/8/1
N2 - Purpose: To evaluate the feasibility of the multimodal interdisciplinary rehabilitation programme HAPPY, targeting patients with haematological malignancy and undergoing allogeneic non-myeloablative haematopoietic stem cell transplantation (NMA-HSCT). Method: A single arm longitudinal design was applied to test the feasibility of the 6-month HAPPY programme, which consisted of motivational interviewing dialogues, individual supervised physical exercise training, relaxation exercises, nutritional counselling, and home assignments. The feasibility measures included acceptability, fidelity, exposure, practicability, and safety. Descriptive statistics were conducted. Results: From November 2018 to January 2020, thirty patients (mean age (SD) 64.1 (6.5)) were enrolled in HAPPY, of whom 18 patients completed the programme. Acceptance was 88%; attrition 40%; fidelity was 80%–100% for all HAPPY elements except phone calls; exposure of HAPPY elements at the hospital reflected individual differences but was acceptable, whereas exposure of HAPPY elements at home was low. Planning of HAPPY for the individual patient was time consuming, and patients were dependent of reminders and incites from the health care professionals. Conclusion: Most elements of the rehabilitation programme HAPPY were feasible. Yet, HAPPY will benefit from further development and simplifications before an effectiveness study can be conducted, especially regarding improvement of the intervention elements supporting patients at home.
AB - Purpose: To evaluate the feasibility of the multimodal interdisciplinary rehabilitation programme HAPPY, targeting patients with haematological malignancy and undergoing allogeneic non-myeloablative haematopoietic stem cell transplantation (NMA-HSCT). Method: A single arm longitudinal design was applied to test the feasibility of the 6-month HAPPY programme, which consisted of motivational interviewing dialogues, individual supervised physical exercise training, relaxation exercises, nutritional counselling, and home assignments. The feasibility measures included acceptability, fidelity, exposure, practicability, and safety. Descriptive statistics were conducted. Results: From November 2018 to January 2020, thirty patients (mean age (SD) 64.1 (6.5)) were enrolled in HAPPY, of whom 18 patients completed the programme. Acceptance was 88%; attrition 40%; fidelity was 80%–100% for all HAPPY elements except phone calls; exposure of HAPPY elements at the hospital reflected individual differences but was acceptable, whereas exposure of HAPPY elements at home was low. Planning of HAPPY for the individual patient was time consuming, and patients were dependent of reminders and incites from the health care professionals. Conclusion: Most elements of the rehabilitation programme HAPPY were feasible. Yet, HAPPY will benefit from further development and simplifications before an effectiveness study can be conducted, especially regarding improvement of the intervention elements supporting patients at home.
KW - Cancer
KW - Haematological neoplasms
KW - Motivational interviewing
KW - Multidisciplinary
KW - Peer-support
KW - Physical exercise training
KW - Relaxation exercise
KW - Supportive care
KW - Survivorship care
KW - Telemedicine
UR - http://www.scopus.com/inward/record.url?scp=85161678000&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.ejon.2023.102339
DO - https://doi.org/10.1016/j.ejon.2023.102339
M3 - Article
C2 - 37327555
SN - 1462-3889
VL - 65
JO - European Journal of Oncology Nursing
JF - European Journal of Oncology Nursing
M1 - 102339
ER -