A novel frequency domain fluorescence technique for determination of triplet decay times

H. J. Sterenborg; M. E. Janson; M. J. van Gemert

doi:https://doi.org/10.1088/0031-9155/44/5/323

A novel frequency domain fluorescence technique for determination of triplet decay times

H. J. Sterenborg, M. E. Janson, M. J. van Gemert

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Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

Abstract

Frequency domain fluorescence measurement using two diode lasers with amplitude modulation in the kHz range yields a signal component at the sum frequency. This intermodulation phenomenon was observed in an aqueous solution of haematoporphyrin (HP) and could be related to triplet state population kinetics. This indirect measurement technique may allow triplet decay time measurement during photodynamic therapy (PDT) enabling monitoring of the type II phototoxic damage rate

Original language	English
Pages (from-to)	1419-1426
Journal	Physics in medicine and biology
Volume	44
Issue number	5
DOIs	https://doi.org/10.1088/0031-9155/44/5/323
Publication status	Published - 1999

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https://doi.org/10.1088/0031-9155/44/5/323

Cite this

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title = "A novel frequency domain fluorescence technique for determination of triplet decay times",

abstract = "Frequency domain fluorescence measurement using two diode lasers with amplitude modulation in the kHz range yields a signal component at the sum frequency. This intermodulation phenomenon was observed in an aqueous solution of haematoporphyrin (HP) and could be related to triplet state population kinetics. This indirect measurement technique may allow triplet decay time measurement during photodynamic therapy (PDT) enabling monitoring of the type II phototoxic damage rate",

author = "Sterenborg, {H. J.} and Janson, {M. E.} and {van Gemert}, {M. J.}",

year = "1999",

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AU - Sterenborg, H. J.

AU - Janson, M. E.

AU - van Gemert, M. J.

PY - 1999

Y1 - 1999

N2 - Frequency domain fluorescence measurement using two diode lasers with amplitude modulation in the kHz range yields a signal component at the sum frequency. This intermodulation phenomenon was observed in an aqueous solution of haematoporphyrin (HP) and could be related to triplet state population kinetics. This indirect measurement technique may allow triplet decay time measurement during photodynamic therapy (PDT) enabling monitoring of the type II phototoxic damage rate

AB - Frequency domain fluorescence measurement using two diode lasers with amplitude modulation in the kHz range yields a signal component at the sum frequency. This intermodulation phenomenon was observed in an aqueous solution of haematoporphyrin (HP) and could be related to triplet state population kinetics. This indirect measurement technique may allow triplet decay time measurement during photodynamic therapy (PDT) enabling monitoring of the type II phototoxic damage rate

U2 - https://doi.org/10.1088/0031-9155/44/5/323

DO - https://doi.org/10.1088/0031-9155/44/5/323

M3 - Article

C2 - 10368028

SN - 0031-9155

VL - 44

SP - 1419

EP - 1426

JO - Physics in medicine and biology

JF - Physics in medicine and biology

IS - 5

ER -