Abstract
In two siblings with systemic lupus erythematosus (SLE), who experienced two episodes of psychosis each, a longitudinal study of autoantibodies, including antibodies to ribosomal P proteins, is described. In two of three evaluable periods of 15 weeks antedating psychosis a rise followed by a spontaneous drop in anti-P levels was recorded. In the third period antibodies to ribosomal protein P were absent. It is concluded that results with single samples are not informative, and that frequent measurement of antibodies to ribosomal protein P in patients with SLE may have limited predictive value for psychosis
Original language | English |
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Pages (from-to) | 779-782 |
Journal | Annals of the rheumatic diseases |
Volume | 49 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1990 |