A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

C. Erik Hack; Gert Jan Wolbink; Caspar Schalkwijk; Han Speijer; Willem Th Hermens; Henk D. Van Den Bosch

doi:https://doi.org/10.1016/S0167-5699(97)01002-5

A role for secretory phospholipase A₂ and C-reactive protein in the removal of injured cells

C. Erik Hack, Gert Jan Wolbink, Caspar Schalkwijk, Han Speijer, Willem Th Hermens, Henk D. Van Den Bosch

Research output: Contribution to journal › Comment/Letter to the editor › Academic

168 Citations (Scopus)

Abstract

The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A₂ and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	Immunology today
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/S0167-5699(97)01002-5
Publication status	Published - Mar 1997

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Cite this

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abstract = "The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.",

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AU - Hack, C. Erik

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AU - Schalkwijk, Caspar

AU - Speijer, Han

AU - Hermens, Willem Th

AU - Van Den Bosch, Henk D.

PY - 1997/3

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AB - The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

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DO - https://doi.org/10.1016/S0167-5699(97)01002-5

M3 - Comment/Letter to the editor

C2 - 9078682

SN - 0167-5699

VL - 18

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JF - Immunology today

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ER -

A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

Abstract

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A role for secretory phospholipase A₂ and C-reactive protein in the removal of injured cells