A space-occupying lesion of the skull base, masked by nasopharyngeal lymphatic tissue hypertrophy and causing cranial nerve dysfunction in an HIV-infected patient

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Patients infected with HIV are at increased risk of developing lymphoma. The lymphomas often involve extranodal sites and +/-90% are of B-cell phenotype. We describe an HIV-infected patient with unilateral multiple cranial nerve dysfunction, most likely as a result of a nasopharyngeal B-cell non-Hodgkin's lymphoma in which early histologic confirmation of the diagnosis was delayed by the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy. It is of practical importance to recognize non-Hodgkin's lymphoma as a cause of cranial nerve dysfunction and to be aware of the possibility and the implications of the simultaneous presence of nasopharyngeal lymphatic tissue hypertrophy in HIV-infected patients
Original languageEnglish
Pages (from-to)164-166
Number of pages3
JournalAnnals of Hematology
Issue number3
Publication statusPublished - Mar 2002


  • Cranial Nerve Diseases/etiology
  • Fatal Outcome
  • Female
  • HIV Infections/complications
  • Humans
  • Lymphoma, Non-Hodgkin/complications
  • Magnetic Resonance Imaging
  • Middle Aged
  • Nasopharyngeal Neoplasms/complications
  • Skull Base Neoplasms/complications

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