A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1

Elisa Giovannetti; Leticia G. Leon; Valentina E. Gomez; Paolo A. Zucali; Filippo Minutolo; Godefridus J. Peters

doi:https://doi.org/10.1080/15257770.2016.1149193

A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1

Elisa Giovannetti, Leticia G. Leon, Valentina E. Gomez, Paolo A. Zucali, Filippo Minutolo, Godefridus J. Peters

Medical oncology laboratory (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Original language	English
Pages (from-to)	643-651
Journal	Nucleosides, Nucleotides and Nucleic Acids
Volume	35
Issue number	10-12
DOIs	https://doi.org/10.1080/15257770.2016.1149193
Publication status	Published - 2016

Keywords

Anticancer nucleosides
LDH
gemcitabine
human equilibrative transporter-1
mechanisms of action studies
mesothelioma

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https://doi.org/10.1080/15257770.2016.1149193

Cite this

Giovannetti, E., Leon, L. G., Gomez, V. E., Zucali, P. A., Minutolo, F., & Peters, G. J. (2016). A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1. Nucleosides, Nucleotides and Nucleic Acids, 35(10-12), 643-651. https://doi.org/10.1080/15257770.2016.1149193

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keywords = "Anticancer nucleosides, LDH, gemcitabine, human equilibrative transporter-1, mechanisms of action studies, mesothelioma",

author = "Elisa Giovannetti and Leon, {Leticia G.} and Gomez, {Valentina E.} and Zucali, {Paolo A.} and Filippo Minutolo and Peters, {Godefridus J.}",

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Giovannetti, E, Leon, LG, Gomez, VE, Zucali, PA, Minutolo, F & Peters, GJ 2016, 'A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1', Nucleosides, Nucleotides and Nucleic Acids, vol. 35, no. 10-12, pp. 643-651. https://doi.org/10.1080/15257770.2016.1149193

A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1. / Giovannetti, Elisa; Leon, Leticia G.; Gomez, Valentina E. et al.
In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 35, No. 10-12, 2016, p. 643-651.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1

AU - Giovannetti, Elisa

AU - Leon, Leticia G.

AU - Gomez, Valentina E.

AU - Zucali, Paolo A.

AU - Minutolo, Filippo

AU - Peters, Godefridus J.

PY - 2016

Y1 - 2016

KW - Anticancer nucleosides

KW - LDH

KW - gemcitabine

KW - human equilibrative transporter-1

KW - mechanisms of action studies

KW - mesothelioma

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DO - https://doi.org/10.1080/15257770.2016.1149193

M3 - Article

C2 - 27906635

SN - 1525-7770

VL - 35

SP - 643

EP - 651

JO - Nucleosides, Nucleotides and Nucleic Acids

JF - Nucleosides, Nucleotides and Nucleic Acids

IS - 10-12

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Giovannetti E, Leon LG, Gomez VE, Zucali PA, Minutolo F, Peters GJ. A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1. Nucleosides, Nucleotides and Nucleic Acids. 2016;35(10-12):643-651. doi: https://doi.org/10.1080/15257770.2016.1149193