Activation of cytotoxic lymphocytes in patients with scrub typhus

Maaike de Fost; Wirongrong Chierakul; Kriangsak Pimda; Arjen M. Dondorp; Nicholas J. White; Tom van der Poll

Activation of cytotoxic lymphocytes in patients with scrub typhus

Maaike de Fost, Wirongrong Chierakul, Kriangsak Pimda, Arjen M. Dondorp, Nicholas J. White, Tom van der Poll

Research output: Contribution to journal › Article › Academic › peer-review

35 Citations (Scopus)

Abstract

Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus

Original language	English
Pages (from-to)	465-467
Journal	American journal of tropical medicine and hygiene
Volume	72
Issue number	4
Publication status	Published - 2005

Cite this

@article{214ac7f4011a4beaa5a8391c71a4f494,

title = "Activation of cytotoxic lymphocytes in patients with scrub typhus",

abstract = "Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus",

author = "{de Fost}, Maaike and Wirongrong Chierakul and Kriangsak Pimda and Dondorp, {Arjen M.} and White, {Nicholas J.} and {van der Poll}, Tom",

year = "2005",

language = "English",

volume = "72",

pages = "465--467",

journal = "American journal of tropical medicine and hygiene",

issn = "0002-9637",

publisher = "American Society of Tropical Medicine and Hygiene",

number = "4",

}

TY - JOUR

T1 - Activation of cytotoxic lymphocytes in patients with scrub typhus

AU - de Fost, Maaike

AU - Chierakul, Wirongrong

AU - Pimda, Kriangsak

AU - Dondorp, Arjen M.

AU - White, Nicholas J.

AU - van der Poll, Tom

PY - 2005

Y1 - 2005

N2 - Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus

AB - Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus

M3 - Article

C2 - 15827287

SN - 0002-9637

VL - 72

SP - 465

EP - 467

JO - American journal of tropical medicine and hygiene

JF - American journal of tropical medicine and hygiene

IS - 4

ER -