TY - JOUR
T1 - Acute Motor and Sensory Axonal Neuropathy in LEOPARD Syndrome
AU - Beukers, Richard J.
AU - van Bellegem, Annemarie C. M.
AU - Gruppen, Mariken
AU - Overweg-Plandsoen, Wouterina C. G.
AU - Vermeulen, Marinus
PY - 2010
Y1 - 2010
N2 - A case of acute predominantly axonal motor and sensory neuropathy (AMSAN) is reported in a 16-year-old boy with LEOPARD syndrome (the acronym represents lentigines, ECG conduction abnormalities, ocular hypertelorism, pulmonic stenosis, abnormal genitalia, retardation of growth, and sensorineural deafness). The presentation was atypical for acute motor and sensory axonal neuropathy, in that this patient had progression of symptoms of more than 4 weeks and there were signs of reinnervation in the acute phase. Treatment response to intravenous immunoglobulins was excellent. In patients with LEOPARD syndrome and acute neuropathies, treatment with intravenous immunoglobulins should be considered. (C) 2010 by Elsevier Inc. All rights reserved
AB - A case of acute predominantly axonal motor and sensory neuropathy (AMSAN) is reported in a 16-year-old boy with LEOPARD syndrome (the acronym represents lentigines, ECG conduction abnormalities, ocular hypertelorism, pulmonic stenosis, abnormal genitalia, retardation of growth, and sensorineural deafness). The presentation was atypical for acute motor and sensory axonal neuropathy, in that this patient had progression of symptoms of more than 4 weeks and there were signs of reinnervation in the acute phase. Treatment response to intravenous immunoglobulins was excellent. In patients with LEOPARD syndrome and acute neuropathies, treatment with intravenous immunoglobulins should be considered. (C) 2010 by Elsevier Inc. All rights reserved
U2 - https://doi.org/10.1016/j.pediatrneurol.2009.12.001
DO - https://doi.org/10.1016/j.pediatrneurol.2009.12.001
M3 - Article
C2 - 20304339
SN - 0887-8994
VL - 42
SP - 301
EP - 303
JO - Pediatric neurology
JF - Pediatric neurology
IS - 4
ER -