Adjuvant radiotherapy in patients with vulvar cancer and one intra capsular lymph node metastasis is not beneficial

G. Fons; S. M. A. Groenen; M. H. M. Oonk; A. C. Ansink; A. G. J. van der Zee; M. P. M. Burger; L. J. A. Stalpers; J. van der Velden

doi:https://doi.org/10.1016/j.ygyno.2009.05.017

Adjuvant radiotherapy in patients with vulvar cancer and one intra capsular lymph node metastasis is not beneficial

G. Fons, S. M. A. Groenen, M. H. M. Oonk, A. C. Ansink, A. G. J. van der Zee, M. P. M. Burger, L. J. A. Stalpers, J. van der Velden

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Abstract

Aim of the study. The aim of the study was to analyze the benefit from adjuvant radiotherapy in patients with vulvar cancer and a single positive node without extra capsular spread. Materials and methods. The Study population comprised data of 75 patients with vulvar cancer and one lymph node metastasis. The patients were treated in three different university centers in Amsterdam, Groningen and Rotterdam between 1984 and 2005. Results. Out of 75 patients, 31 (41%) were treated with adjuvant radiotherapy. Both disease-free survival (DFS) and disease-specific survival (DSS) were comparable between the groups who did and who did not receive adjuvant radiotherapy (HR 0.98, 95% CI 0.45-2.14, p=0.97 and HR = 1.02, 95% CI 0.42-2.47, p = 0.96). Conclusion. We could not demonstrate any beneficial effect of adjuvant radiotherapy in the group Of patients with one intra capsular metastasis. (C) 2009 Elsevier Inc. All rights reserved

Original language	English
Pages (from-to)	343-345
Journal	Gynecologic Oncology
Volume	114
Issue number	2
DOIs	https://doi.org/10.1016/j.ygyno.2009.05.017
Publication status	Published - 2009

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https://doi.org/10.1016/j.ygyno.2009.05.017

Cite this

@article{62fe653ca40a4aad987d387a04a76e14,

title = "Adjuvant radiotherapy in patients with vulvar cancer and one intra capsular lymph node metastasis is not beneficial",

abstract = "Aim of the study. The aim of the study was to analyze the benefit from adjuvant radiotherapy in patients with vulvar cancer and a single positive node without extra capsular spread. Materials and methods. The Study population comprised data of 75 patients with vulvar cancer and one lymph node metastasis. The patients were treated in three different university centers in Amsterdam, Groningen and Rotterdam between 1984 and 2005. Results. Out of 75 patients, 31 (41%) were treated with adjuvant radiotherapy. Both disease-free survival (DFS) and disease-specific survival (DSS) were comparable between the groups who did and who did not receive adjuvant radiotherapy (HR 0.98, 95% CI 0.45-2.14, p=0.97 and HR = 1.02, 95% CI 0.42-2.47, p = 0.96). Conclusion. We could not demonstrate any beneficial effect of adjuvant radiotherapy in the group Of patients with one intra capsular metastasis. (C) 2009 Elsevier Inc. All rights reserved",

author = "G. Fons and Groenen, {S. M. A.} and Oonk, {M. H. M.} and Ansink, {A. C.} and {van der Zee}, {A. G. J.} and Burger, {M. P. M.} and Stalpers, {L. J. A.} and {van der Velden}, J.",

year = "2009",

doi = "https://doi.org/10.1016/j.ygyno.2009.05.017",

language = "English",

volume = "114",

pages = "343--345",

journal = "Gynecologic Oncology",

issn = "0090-8258",

publisher = "Academic Press Inc.",

number = "2",

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TY - JOUR

T1 - Adjuvant radiotherapy in patients with vulvar cancer and one intra capsular lymph node metastasis is not beneficial

AU - Fons, G.

AU - Groenen, S. M. A.

AU - Oonk, M. H. M.

AU - Ansink, A. C.

AU - van der Zee, A. G. J.

AU - Burger, M. P. M.

AU - Stalpers, L. J. A.

AU - van der Velden, J.

PY - 2009

Y1 - 2009

N2 - Aim of the study. The aim of the study was to analyze the benefit from adjuvant radiotherapy in patients with vulvar cancer and a single positive node without extra capsular spread. Materials and methods. The Study population comprised data of 75 patients with vulvar cancer and one lymph node metastasis. The patients were treated in three different university centers in Amsterdam, Groningen and Rotterdam between 1984 and 2005. Results. Out of 75 patients, 31 (41%) were treated with adjuvant radiotherapy. Both disease-free survival (DFS) and disease-specific survival (DSS) were comparable between the groups who did and who did not receive adjuvant radiotherapy (HR 0.98, 95% CI 0.45-2.14, p=0.97 and HR = 1.02, 95% CI 0.42-2.47, p = 0.96). Conclusion. We could not demonstrate any beneficial effect of adjuvant radiotherapy in the group Of patients with one intra capsular metastasis. (C) 2009 Elsevier Inc. All rights reserved

AB - Aim of the study. The aim of the study was to analyze the benefit from adjuvant radiotherapy in patients with vulvar cancer and a single positive node without extra capsular spread. Materials and methods. The Study population comprised data of 75 patients with vulvar cancer and one lymph node metastasis. The patients were treated in three different university centers in Amsterdam, Groningen and Rotterdam between 1984 and 2005. Results. Out of 75 patients, 31 (41%) were treated with adjuvant radiotherapy. Both disease-free survival (DFS) and disease-specific survival (DSS) were comparable between the groups who did and who did not receive adjuvant radiotherapy (HR 0.98, 95% CI 0.45-2.14, p=0.97 and HR = 1.02, 95% CI 0.42-2.47, p = 0.96). Conclusion. We could not demonstrate any beneficial effect of adjuvant radiotherapy in the group Of patients with one intra capsular metastasis. (C) 2009 Elsevier Inc. All rights reserved

U2 - https://doi.org/10.1016/j.ygyno.2009.05.017

DO - https://doi.org/10.1016/j.ygyno.2009.05.017

M3 - Article

C2 - 19481242

SN - 0090-8258

VL - 114

SP - 343

EP - 345

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 2

ER -