Alpha-oxidation

Gerbert A. Jansen, Ronald J. A. Wanders

Research output: Contribution to journalReview articleAcademicpeer-review

85 Citations (Scopus)

Abstract

Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched chain fatty acid, which is a constituent of the human diet. The presence of the 3-methyl group of phytanic acid prevents degradation by beta-oxidation. Instead, the terminal carboxyl group is first removed by alpha-oxidation. The mechanism of the alpha-oxidation pathway and the enzymes involved are described in this review
Original languageEnglish
Pages (from-to)1403-1412
JournalBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Volume1763
Issue number12
DOIs
Publication statusPublished - 2006

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