Alternative macroautophagic pathways

Katrin Juenemann, Eric A. Reits

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)


Macroautophagy is a bulk degradation process that mediates the clearance of long-lived proteins, aggregates, or even whole organelles. This process includes the formation of autophagosomes, double-membrane structures responsible for delivering cargo to lysosomes for degradation. Currently, other alternative autophagy pathways have been described, which are independent of macroautophagic key players like Atg5 and Beclin 1 or the lipidation of LC3. In this review, we highlight recent insights in indentifying and understanding the molecular mechanism responsible for alternative autophagic pathways
Original languageEnglish
Pages (from-to)189794
JournalInternational Journal of Cell Biology
Publication statusPublished - 2012

Cite this