TY - JOUR
T1 - An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group
AU - Kunadian, Vijay
AU - Chieffo, Alaide
AU - Camici, Paolo G.
AU - Berry, Colin
AU - Escaned, Javier
AU - Maas, Angela H. E. M.
AU - Prescott, Eva
AU - Karam, Nicole
AU - Appelman, Yolande
AU - Fraccaro, Chiara
AU - Louise Buchanan, Gill
AU - Manzo-Silberman, Stephane
AU - Al-Lamee, Rasha
AU - Regar, Evelyn
AU - Lansky, Alexandra
AU - Abbott, J. Dawn
AU - Badimon, Lina
AU - Duncker, Dirk J.
AU - Mehran, Roxana
AU - Capodanno, Davide
AU - Baumbach, Andreas
PY - 2020/10/1
Y1 - 2020/10/1
N2 - This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
AB - This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094219929&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/32626906
UR - http://www.scopus.com/inward/record.url?scp=85094219929&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/eurheartj/ehaa503
DO - https://doi.org/10.1093/eurheartj/ehaa503
M3 - Article
C2 - 32626906
SN - 0195-668X
VL - 41
SP - 3504
EP - 3520
JO - European Heart journal
JF - European Heart journal
IS - 37
ER -