TY - JOUR
T1 - Anaemia, iron deficiency and susceptibility to infection in children in sub-Saharan Africa, guideline dilemmas
AU - Jonker, Femkje A. M.
AU - te Poel, Elodie
AU - Bates, Imelda
AU - Boele van Hensbroek, Michael
PY - 2017
Y1 - 2017
N2 - Globally, anaemia, iron deficiency and infections are responsible for a majority of the morbidity and mortality that occurs among children. As iron is essential for erythropoiesis and the human immune system, as well as a crucial element for many pathogens, these three conditions often interact. This article considers the question - have the studies conducted so far unravelled the potential complex interaction between these factors sufficiently enough to be able to develop universally applicable guidelines about iron treatment in children? It is possible, however, that the area is too complex and diverse, with many sub-populations, and that not universal, but tailor-made guidelines are needed based on some agreed principles
AB - Globally, anaemia, iron deficiency and infections are responsible for a majority of the morbidity and mortality that occurs among children. As iron is essential for erythropoiesis and the human immune system, as well as a crucial element for many pathogens, these three conditions often interact. This article considers the question - have the studies conducted so far unravelled the potential complex interaction between these factors sufficiently enough to be able to develop universally applicable guidelines about iron treatment in children? It is possible, however, that the area is too complex and diverse, with many sub-populations, and that not universal, but tailor-made guidelines are needed based on some agreed principles
U2 - https://doi.org/10.1111/bjh.14593
DO - https://doi.org/10.1111/bjh.14593
M3 - Review article
C2 - 28397964
SN - 0007-1048
VL - 177
SP - 878
EP - 883
JO - British journal of haematology
JF - British journal of haematology
IS - 6
ER -