TY - JOUR
T1 - Antineoplastic Drug Contamination on the Outside of Prepared Infusion Bags
AU - Breukels, Oscar
AU - van der Gronde, Toon
AU - Simons-Sanders, Kathleen
AU - Crul, Mirjam
PY - 2018
Y1 - 2018
N2 - Eight Dutch hospital pharmacies took wipe samples of prepared infusion bags containing 5 fluorouracil just before distribution to the wards. The samples were tested with high-performance liquid chromatography and triple quadrupole mass spectroscopy. The limit of detection was 10 ng per swipe. None of the 146 samples had a detectable amount of 5-fluorouracil. The outside of infusion bags containing antineoplastic drugs prepared in these eight Dutch hospital pharmacies were not contaminated and, therefore, were not a risk factor with regard to exposure of hospital workers to antineoplastic drugs.
AB - Eight Dutch hospital pharmacies took wipe samples of prepared infusion bags containing 5 fluorouracil just before distribution to the wards. The samples were tested with high-performance liquid chromatography and triple quadrupole mass spectroscopy. The limit of detection was 10 ng per swipe. None of the 146 samples had a detectable amount of 5-fluorouracil. The outside of infusion bags containing antineoplastic drugs prepared in these eight Dutch hospital pharmacies were not contaminated and, therefore, were not a risk factor with regard to exposure of hospital workers to antineoplastic drugs.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053720184&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30021191
M3 - Article
C2 - 30021191
SN - 1092-4221
VL - 22
SP - 345
EP - 349
JO - International journal of pharmaceutical compounding
JF - International journal of pharmaceutical compounding
IS - 4
ER -