Approaches towards the synthesis of fluoro(cyclo)alkylamines

A. D. Windhorst, L. Bechger, G. W.M. Visser, W. P.M.B. Menge, R. Leurs, H. Timmerman, J. D.M. Herscheid

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7 Citations (Scopus)


The synthesis of fluoro(cyclo)alkylamines 1-amino-6-fluorohexane (1), 1-amino-7-fluoroheptane (2), cis/trans-4-fluorocyclohexylamine (3a,b) and cis-4-fluoromethylcyclohexylamine (4) has been investigated for use as synthons for histamine receptor ligands for use in PET.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalJournal of Fluorine Chemistry
Issue number1
Publication statusPublished - 1 Sept 1996


  • Fluorinated cyclohexylamines
  • Fluorination
  • Rapid synthesis
  • ω-Fluoroalkylamines

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