Approximate sample size calculations with microarray data: an illustration

José A. Ferreira; Aeilko Zwinderman

doi:https://doi.org/10.2202/1544-6115.1227

Approximate sample size calculations with microarray data: an illustration

José A. Ferreira, Aeilko Zwinderman

Research output: Contribution to journal › Article › Academic › peer-review

35 Citations (Scopus)

Abstract

We outline a method of sample size calculation in microarray experiments on the basis of pilot data and illustrate its practical application with both simulated and real data. The method was shown to be consistent (as the number of 'probed genes' tends to infinity) under general conditions in an earlier, more 'theoretical' companion paper. Its implementation requires the values of test statistics, the sample size with which the statistics are computed, and the knowledge of their distribution under the null hypothesis

Original language	English
Pages (from-to)	Article25
Journal	Statistical Applications in Genetics and Molecular Biology
Volume	5
DOIs	https://doi.org/10.2202/1544-6115.1227
Publication status	Published - 2006

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https://doi.org/10.2202/1544-6115.1227

Cite this

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