TY - JOUR
T1 - Associations between Disordered Eating Behaviors and HbA1c in Young People with Type 1 Diabetes
T2 - A Systematic Review and Meta-analysis
AU - Marks, Kevin P.
AU - Aalders, Jori
AU - Liu, Shengxin
AU - Broadley, Melanie
AU - Thastum, Mikael
AU - Jensen, Morten B.
AU - Ibfelt, Else H.
AU - Birkebaek, Niels H.
AU - Pouwer, Frans
N1 - Publisher Copyright: © 2024 Bentham Science Publishers.
PY - 2024
Y1 - 2024
N2 - Background: In type 1 diabetes, disordered eating behaviors (DEB) can adversely impact HbA 1c. Diabetes-adapted DEB questionnaires assess intentional insulin omission, whereas generic questionnaires do not. Given the number of studies describing DEB-HbA 1c associations pub-lished over the past decade, an updated systematic review is warranted. Objective: The study aimed to examine the associations between DEBs assessed by generic and di-abetes-adapted questionnaires (and subscales) and HbA 1c among young people (<29 years) with type 1 diabetes. Methods: A systematic search was conducted in PubMed, Embase, PsycInfo, and CINAHL data-bases. Observational studies examining associations between DEB as assessed by questionnaires and HbA 1c were included. Publication information, DEB and HbA 1c characteristics, and DEB-HbA 1c associations were extracted. Hedges’ g was calculated for mean HbA 1c differences between groups with and without DEB. Results: The systematic search yielded 733 reports, of which 39 reports representing 35 unique studies met the inclusion criteria. Nineteen studies assessing DEB by diabetes-adapted questionnaires (n=5,795) and seven using generic questionnaires (n=2,162) provided data for meta-analysis. For diabetes-adapted questionnaires, DEB was associated with higher HbA 1c (g=0.62 CI=0.52; 0.73) with a similar effect size when restricted to validated questionnaires (g=0.61; CI=0.50; 0.73). DEB was not associated with HbA 1c for generic questionnaires (g=0.19; CI=-0.17; 0.55), but significantly associated with higher HbA 1c for validated generic questionnaires (g=0.32; 95% CI=0.16-0.48). Participant and HbA 1c collection characteristics were often inadequately described. Conclusion: Diabetes-adapted DEB questionnaires should be used in youth with type 1 diabetes because they capture intentional insulin omission and are more strongly associated with HbA 1c than generic DEB questionnaires.
AB - Background: In type 1 diabetes, disordered eating behaviors (DEB) can adversely impact HbA 1c. Diabetes-adapted DEB questionnaires assess intentional insulin omission, whereas generic questionnaires do not. Given the number of studies describing DEB-HbA 1c associations pub-lished over the past decade, an updated systematic review is warranted. Objective: The study aimed to examine the associations between DEBs assessed by generic and di-abetes-adapted questionnaires (and subscales) and HbA 1c among young people (<29 years) with type 1 diabetes. Methods: A systematic search was conducted in PubMed, Embase, PsycInfo, and CINAHL data-bases. Observational studies examining associations between DEB as assessed by questionnaires and HbA 1c were included. Publication information, DEB and HbA 1c characteristics, and DEB-HbA 1c associations were extracted. Hedges’ g was calculated for mean HbA 1c differences between groups with and without DEB. Results: The systematic search yielded 733 reports, of which 39 reports representing 35 unique studies met the inclusion criteria. Nineteen studies assessing DEB by diabetes-adapted questionnaires (n=5,795) and seven using generic questionnaires (n=2,162) provided data for meta-analysis. For diabetes-adapted questionnaires, DEB was associated with higher HbA 1c (g=0.62 CI=0.52; 0.73) with a similar effect size when restricted to validated questionnaires (g=0.61; CI=0.50; 0.73). DEB was not associated with HbA 1c for generic questionnaires (g=0.19; CI=-0.17; 0.55), but significantly associated with higher HbA 1c for validated generic questionnaires (g=0.32; 95% CI=0.16-0.48). Participant and HbA 1c collection characteristics were often inadequately described. Conclusion: Diabetes-adapted DEB questionnaires should be used in youth with type 1 diabetes because they capture intentional insulin omission and are more strongly associated with HbA 1c than generic DEB questionnaires.
KW - Type 1 diabetes
KW - adolescent diabe-tes
KW - eating behaviors
KW - glycemic control
KW - hemoglobin A1c (HbA )
KW - pediatric diabetes
UR - http://www.scopus.com/inward/record.url?scp=85185458884&partnerID=8YFLogxK
U2 - 10.2174/1573399820666230822095939
DO - 10.2174/1573399820666230822095939
M3 - Article
C2 - 37608674
SN - 1573-3998
VL - 20
JO - Current diabetes reviews
JF - Current diabetes reviews
IS - 4
M1 - e220823220144
ER -