Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)

Akke Vellinga; A. Zawiejska; J. Harreiter; B. Buckley; G. Di Cianni; A. Lapolla; R. Corcoy; D. Simmons; J. M. Adelantado; P. Damm; G. Desoye; R. Devlieger; D. Hill; A. Kautzky-Willer; M. Klemetti; E. Mathiesen; P. Rebollo; F. Snoek; M. Tikkanen; D. Timmerman; A. van Assche; M. van Poppel; E. Wender-Oegowska; F. Dunne

doi:https://doi.org/10.5402/2012/424010

Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)

Akke Vellinga, A. Zawiejska, J. Harreiter, B. Buckley, G. Di Cianni, A. Lapolla, R. Corcoy, D. Simmons, J. M. Adelantado, P. Damm, G. Desoye, R. Devlieger, D. Hill, A. Kautzky-Willer, M. Klemetti, E. Mathiesen, P. Rebollo, F. Snoek, M. Tikkanen, D. TimmermanA. van Assche, M. van Poppel, E. Wender-Oegowska, F. Dunne

Amsterdam UMC

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objective. Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods. Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results. Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m(2)) and GDM were independent risk factors of neonatal morbidities. Conclusions. Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation

Original language	English
Pages (from-to)	424010
Journal	ISRN obesity
Volume	2012
DOIs	https://doi.org/10.5402/2012/424010
Publication status	Published - 2012

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https://doi.org/10.5402/2012/424010

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Vellinga, A., Zawiejska, A., Harreiter, J., Buckley, B., Di Cianni, G., Lapolla, A., Corcoy, R., Simmons, D., Adelantado, J. M., Damm, P., Desoye, G., Devlieger, R., Hill, D., Kautzky-Willer, A., Klemetti, M., Mathiesen, E., Rebollo, P., Snoek, F., Tikkanen, M., ... Dunne, F. (2012). Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention). ISRN obesity, 2012, 424010. https://doi.org/10.5402/2012/424010

Vellinga, Akke ; Zawiejska, A. ; Harreiter, J. et al. / Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention). In: ISRN obesity. 2012 ; Vol. 2012. pp. 424010.

@article{f73879fa42f14c8eb07c7a6bc7af05af,

title = "Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)",

abstract = "Objective. Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods. Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results. Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m(2)) and GDM were independent risk factors of neonatal morbidities. Conclusions. Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation",

author = "Akke Vellinga and A. Zawiejska and J. Harreiter and B. Buckley and {Di Cianni}, G. and A. Lapolla and R. Corcoy and D. Simmons and Adelantado, {J. M.} and P. Damm and G. Desoye and R. Devlieger and D. Hill and A. Kautzky-Willer and M. Klemetti and E. Mathiesen and P. Rebollo and F. Snoek and M. Tikkanen and D. Timmerman and {van Assche}, A. and {van Poppel}, M. and E. Wender-Oegowska and F. Dunne",

year = "2012",

doi = "https://doi.org/10.5402/2012/424010",

language = "English",

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pages = "424010",

journal = "ISRN obesity",

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Vellinga, A, Zawiejska, A, Harreiter, J, Buckley, B, Di Cianni, G, Lapolla, A, Corcoy, R, Simmons, D, Adelantado, JM, Damm, P, Desoye, G, Devlieger, R, Hill, D, Kautzky-Willer, A, Klemetti, M, Mathiesen, E, Rebollo, P, Snoek, F, Tikkanen, M, Timmerman, D, van Assche, A, van Poppel, M, Wender-Oegowska, E & Dunne, F 2012, 'Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)', ISRN obesity, vol. 2012, pp. 424010. https://doi.org/10.5402/2012/424010

Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention). / Vellinga, Akke; Zawiejska, A.; Harreiter, J. et al.
In: ISRN obesity, Vol. 2012, 2012, p. 424010.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)

AU - Vellinga, Akke

AU - Zawiejska, A.

AU - Harreiter, J.

AU - Buckley, B.

AU - Di Cianni, G.

AU - Lapolla, A.

AU - Corcoy, R.

AU - Simmons, D.

AU - Adelantado, J. M.

AU - Damm, P.

AU - Desoye, G.

AU - Devlieger, R.

AU - Hill, D.

AU - Kautzky-Willer, A.

AU - Klemetti, M.

AU - Mathiesen, E.

AU - Rebollo, P.

AU - Snoek, F.

AU - Tikkanen, M.

AU - Timmerman, D.

AU - van Assche, A.

AU - van Poppel, M.

AU - Wender-Oegowska, E.

AU - Dunne, F.

PY - 2012

Y1 - 2012

N2 - Objective. Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods. Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results. Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m(2)) and GDM were independent risk factors of neonatal morbidities. Conclusions. Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation

AB - Objective. Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods. Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results. Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m(2)) and GDM were independent risk factors of neonatal morbidities. Conclusions. Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation

U2 - https://doi.org/10.5402/2012/424010

DO - https://doi.org/10.5402/2012/424010

M3 - Article

C2 - 24527262

SN - 2090-9446

VL - 2012

SP - 424010

JO - ISRN obesity

JF - ISRN obesity

ER -

Vellinga A, Zawiejska A, Harreiter J, Buckley B, Di Cianni G, Lapolla A et al. Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention). ISRN obesity. 2012;2012:424010. doi: https://doi.org/10.5402/2012/424010