Asthma and asthma medication use among 4-year-old offspring of subfertile couples--association with IVF?

Derk B. Kuiper; Jorien Seggers; Pamela Schendelaar; Maaike L. Haadsma; Tessa J. Roseboom; Maas J. Heineman; Mijna Hadders-Algra

doi:https://doi.org/10.1016/j.rbmo.2015.08.002

Asthma and asthma medication use among 4-year-old offspring of subfertile couples--association with IVF?

Derk B. Kuiper, Jorien Seggers, Pamela Schendelaar, Maaike L. Haadsma, Tessa J. Roseboom, Maas J. Heineman, Mijna Hadders-Algra

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

This study evaluated the prevalence of asthma and asthma medication use in 213 4-year-old singletons followed from birth onwards, including three groups of children born following: (i) controlled ovarian hyperstimulation IVF/intracytoplasmic sperm injection (ICSI); (ii) modified natural cycle IVF/ICSI; and (iii) natural conception in subfertile couples. The rate of asthma medication was higher in the ovarian hyperstimulation-IVF/ICSI than in the subfertile group (adjusted odds ratios [aOR]: 1.96 [1.00-3.84]). Time to pregnancy, a proxy for the severity of subfertility, was not associated with asthma and asthma medication. In conclusion, controlled ovarian hyperstimulation-IVF/ICSI is associated with the use of asthma medication in 4-year-old offspring of subfertile couples

Original language	English
Pages (from-to)	711-714
Journal	Reproductive BioMedicine Online
Volume	31
Issue number	5
DOIs	https://doi.org/10.1016/j.rbmo.2015.08.002
Publication status	Published - 2015

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https://doi.org/10.1016/j.rbmo.2015.08.002

Cite this

@article{c8051f2c64234d07a970d22aec2c2eb0,

title = "Asthma and asthma medication use among 4-year-old offspring of subfertile couples--association with IVF?",

abstract = "This study evaluated the prevalence of asthma and asthma medication use in 213 4-year-old singletons followed from birth onwards, including three groups of children born following: (i) controlled ovarian hyperstimulation IVF/intracytoplasmic sperm injection (ICSI); (ii) modified natural cycle IVF/ICSI; and (iii) natural conception in subfertile couples. The rate of asthma medication was higher in the ovarian hyperstimulation-IVF/ICSI than in the subfertile group (adjusted odds ratios [aOR]: 1.96 [1.00-3.84]). Time to pregnancy, a proxy for the severity of subfertility, was not associated with asthma and asthma medication. In conclusion, controlled ovarian hyperstimulation-IVF/ICSI is associated with the use of asthma medication in 4-year-old offspring of subfertile couples",

author = "Kuiper, {Derk B.} and Jorien Seggers and Pamela Schendelaar and Haadsma, {Maaike L.} and Roseboom, {Tessa J.} and Heineman, {Maas J.} and Mijna Hadders-Algra",

year = "2015",

doi = "https://doi.org/10.1016/j.rbmo.2015.08.002",

language = "English",

volume = "31",

pages = "711--714",

journal = "Reproductive BioMedicine Online",

issn = "1472-6483",