Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength

AUTHOR GROUP; CARPA Study Group

doi:https://doi.org/10.1016/j.joca.2013.12.007

Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength

AUTHOR GROUP, CARPA Study Group

Research output: Contribution to journal › Article › Academic › peer-review

45 Citations (Scopus)

Abstract

Objective: To evaluate the mediating role of reduced muscle strength in the relationship between avoidance of activity and limitations in activities in patients with knee or hip osteoarthritis (OA). Methods: A longitudinal cohort study with 5 years follow-up was conducted. Patients with knee or hip OA (n = 288) were recruited at rehabilitation centers and hospitals. Self-reported and performance based limitations in activities, avoidance of activity and muscle strength were assessed at baseline, 1, 2, 3 and 5 years follow-up. Generalized Estimating Equations (GEE) analyses were used to evaluate mediation. Results: In patients with knee OA, reduced knee extensor muscle strength mediated the relationship between avoidance of activity and limitations in activities. In patients with hip OA reduced hip abductor muscle strength mediates the relationship between avoidance of activity and limitations in activities. Conclusion: The results of this longitudinal study support the theory that avoidance of activity leads to deterioration of muscle strength and consequently to more limitations in activities in patients with knee and hip OA. 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved

Original language	English
Pages (from-to)	171-177
Number of pages	7
Journal	Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.joca.2013.12.007
Publication status	Published - Feb 2014

Keywords

Activities of Daily Living
Aged
Aged, 80 and over
Disease Progression
Female
Follow-Up Studies
Humans
Male
Middle Aged
Motor Activity/physiology
Muscle Strength/physiology
Muscle Weakness/etiology
Muscle, Skeletal/physiopathology
Osteoarthritis, Hip/complications
Osteoarthritis, Knee/complications
Pain/etiology
Self Report

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https://doi.org/10.1016/j.joca.2013.12.007

Cite this

AUTHOR GROUP, & CARPA Study Group (2014). Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, 22(2), 171-177. https://doi.org/10.1016/j.joca.2013.12.007

AUTHOR GROUP ; CARPA Study Group. / Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength : a 5 year follow-up study on the mediating role of reduced muscle strength. In: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society. 2014 ; Vol. 22, No. 2. pp. 171-177.

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title = "Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength",

abstract = "Objective: To evaluate the mediating role of reduced muscle strength in the relationship between avoidance of activity and limitations in activities in patients with knee or hip osteoarthritis (OA). Methods: A longitudinal cohort study with 5 years follow-up was conducted. Patients with knee or hip OA (n = 288) were recruited at rehabilitation centers and hospitals. Self-reported and performance based limitations in activities, avoidance of activity and muscle strength were assessed at baseline, 1, 2, 3 and 5 years follow-up. Generalized Estimating Equations (GEE) analyses were used to evaluate mediation. Results: In patients with knee OA, reduced knee extensor muscle strength mediated the relationship between avoidance of activity and limitations in activities. In patients with hip OA reduced hip abductor muscle strength mediates the relationship between avoidance of activity and limitations in activities. Conclusion: The results of this longitudinal study support the theory that avoidance of activity leads to deterioration of muscle strength and consequently to more limitations in activities in patients with knee and hip OA. 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved",

keywords = "Activities of Daily Living, Aged, Aged, 80 and over, Disease Progression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Motor Activity/physiology, Muscle Strength/physiology, Muscle Weakness/etiology, Muscle, Skeletal/physiopathology, Osteoarthritis, Hip/complications, Osteoarthritis, Knee/complications, Pain/etiology, Self Report",

author = "Pisters, {M. F.} and C. Veenhof and {van Dijk}, {G. M.} and J. Dekker and {AUTHOR GROUP} and Anita Beelen and {de Bie}, {Rob M. A.} and Joost Dekker and Lankhorst, {Guustaaf J.} and Frans Nollet and Pisters, {Martijn F.} and Tersteeg, {Irene M.} and Cindy Veenhof and Velseboer, {Daan C.} and {CARPA Study Group}",

year = "2014",

month = feb,

doi = "https://doi.org/10.1016/j.joca.2013.12.007",

language = "English",

volume = "22",

pages = "171--177",

journal = "Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society",

issn = "1063-4584",

publisher = "W.B. Saunders Ltd",

number = "2",

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AUTHOR GROUP & CARPA Study Group 2014, 'Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength', Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, vol. 22, no. 2, pp. 171-177. https://doi.org/10.1016/j.joca.2013.12.007

Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength. / AUTHOR GROUP; CARPA Study Group.
In: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 22, No. 2, 02.2014, p. 171-177.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength

T2 - a 5 year follow-up study on the mediating role of reduced muscle strength

AU - Pisters, M. F.

AU - Veenhof, C.

AU - van Dijk, G. M.

AU - Dekker, J.

AU - AUTHOR GROUP

AU - Beelen, Anita

AU - de Bie, Rob M. A.

AU - Dekker, Joost

AU - Lankhorst, Guustaaf J.

AU - Nollet, Frans

AU - Pisters, Martijn F.

AU - Tersteeg, Irene M.

AU - Veenhof, Cindy

AU - Velseboer, Daan C.

AU - CARPA Study Group

PY - 2014/2

Y1 - 2014/2

N2 - Objective: To evaluate the mediating role of reduced muscle strength in the relationship between avoidance of activity and limitations in activities in patients with knee or hip osteoarthritis (OA). Methods: A longitudinal cohort study with 5 years follow-up was conducted. Patients with knee or hip OA (n = 288) were recruited at rehabilitation centers and hospitals. Self-reported and performance based limitations in activities, avoidance of activity and muscle strength were assessed at baseline, 1, 2, 3 and 5 years follow-up. Generalized Estimating Equations (GEE) analyses were used to evaluate mediation. Results: In patients with knee OA, reduced knee extensor muscle strength mediated the relationship between avoidance of activity and limitations in activities. In patients with hip OA reduced hip abductor muscle strength mediates the relationship between avoidance of activity and limitations in activities. Conclusion: The results of this longitudinal study support the theory that avoidance of activity leads to deterioration of muscle strength and consequently to more limitations in activities in patients with knee and hip OA. 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved

AB - Objective: To evaluate the mediating role of reduced muscle strength in the relationship between avoidance of activity and limitations in activities in patients with knee or hip osteoarthritis (OA). Methods: A longitudinal cohort study with 5 years follow-up was conducted. Patients with knee or hip OA (n = 288) were recruited at rehabilitation centers and hospitals. Self-reported and performance based limitations in activities, avoidance of activity and muscle strength were assessed at baseline, 1, 2, 3 and 5 years follow-up. Generalized Estimating Equations (GEE) analyses were used to evaluate mediation. Results: In patients with knee OA, reduced knee extensor muscle strength mediated the relationship between avoidance of activity and limitations in activities. In patients with hip OA reduced hip abductor muscle strength mediates the relationship between avoidance of activity and limitations in activities. Conclusion: The results of this longitudinal study support the theory that avoidance of activity leads to deterioration of muscle strength and consequently to more limitations in activities in patients with knee and hip OA. 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved

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KW - Aged

KW - Aged, 80 and over

KW - Disease Progression

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Motor Activity/physiology

KW - Muscle Strength/physiology

KW - Muscle Weakness/etiology

KW - Muscle, Skeletal/physiopathology

KW - Osteoarthritis, Hip/complications

KW - Osteoarthritis, Knee/complications

KW - Pain/etiology

KW - Self Report

U2 - https://doi.org/10.1016/j.joca.2013.12.007

DO - https://doi.org/10.1016/j.joca.2013.12.007

M3 - Article

C2 - 24333296

SN - 1063-4584

VL - 22

SP - 171

EP - 177

JO - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

JF - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

IS - 2

ER -

AUTHOR GROUP, CARPA Study Group. Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength: a 5 year follow-up study on the mediating role of reduced muscle strength. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society. 2014 Feb;22(2):171-177. doi: https://doi.org/10.1016/j.joca.2013.12.007