Beneficial effects of ERCP and papillotomy in predicted severe biliary pancreatitis

M. G. H. Besselink; L. P. van Minnen; K. J. van Erpecum; K. Bosscha; H. G. Gooszen

Beneficial effects of ERCP and papillotomy in predicted severe biliary pancreatitis

M. G. H. Besselink, L. P. van Minnen, K. J. van Erpecum, K. Bosscha, H. G. Gooszen

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Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

BACKGROUND/AIMS: Extensive circumstantial evidence indicates that patients with a predicted severe attack of acute biliary pancreatitis (ABP) should undergo an endoscopic retrograde cholangiography with papillotomy (ERC/PT). However, in clinical practice this procedure is not always performed. This study was conducted to compare outcome in patients with and without ERC/PT. METHODOLOGY: Thirty-five of 80 patients admitted with ABP had a predicted severe attack (three or more Ranson criteria). Only in 24 of these 35 patients was an ERC/PT performed. RESULTS: In the ERC/PT group, significantly less pancreatic necrosis (8 vs. 64%, p <0.001) occurred, hospital stay was shorter (median 22 +/- 5 vs. 51 +/- 19 days, P=0.08) and mortality was lower (8 vs. 36%, P=0.01). Twenty-three patients (66%) underwent cholecystectomy after a median period of 10 weeks (range 0-26 weeks) after discharge. During the waiting period, in the ERC/PT group, two patients developed acute cholecystitis whereas recurrent ABP and common bile duct stones occurred in one patient each. CONCLUSIONS: In patients with a predicted severe attack of ABP, performing ERC/PT is associated with less morbidity and lower mortality

Original language	English
Pages (from-to)	37-39
Journal	Hepato-Gastroenterology
Volume	52
Issue number	61
Publication status	Published - 2005

Cite this

@article{cc77e6421a8046d7b25e53b228f29e85,

title = "Beneficial effects of ERCP and papillotomy in predicted severe biliary pancreatitis",

abstract = "BACKGROUND/AIMS: Extensive circumstantial evidence indicates that patients with a predicted severe attack of acute biliary pancreatitis (ABP) should undergo an endoscopic retrograde cholangiography with papillotomy (ERC/PT). However, in clinical practice this procedure is not always performed. This study was conducted to compare outcome in patients with and without ERC/PT. METHODOLOGY: Thirty-five of 80 patients admitted with ABP had a predicted severe attack (three or more Ranson criteria). Only in 24 of these 35 patients was an ERC/PT performed. RESULTS: In the ERC/PT group, significantly less pancreatic necrosis (8 vs. 64%, p <0.001) occurred, hospital stay was shorter (median 22 +/- 5 vs. 51 +/- 19 days, P=0.08) and mortality was lower (8 vs. 36%, P=0.01). Twenty-three patients (66%) underwent cholecystectomy after a median period of 10 weeks (range 0-26 weeks) after discharge. During the waiting period, in the ERC/PT group, two patients developed acute cholecystitis whereas recurrent ABP and common bile duct stones occurred in one patient each. CONCLUSIONS: In patients with a predicted severe attack of ABP, performing ERC/PT is associated with less morbidity and lower mortality",

author = "Besselink, {M. G. H.} and {van Minnen}, {L. P.} and {van Erpecum}, {K. J.} and K. Bosscha and Gooszen, {H. G.}",

year = "2005",

language = "English",

volume = "52",

pages = "37--39",

journal = "Hepato-Gastroenterology",

issn = "0172-6390",

publisher = "H.G.E. Update Medical Publishing Ltd.",

number = "61",

}

TY - JOUR

T1 - Beneficial effects of ERCP and papillotomy in predicted severe biliary pancreatitis

AU - Besselink, M. G. H.

AU - van Minnen, L. P.

AU - van Erpecum, K. J.

AU - Bosscha, K.

AU - Gooszen, H. G.

PY - 2005

Y1 - 2005

N2 - BACKGROUND/AIMS: Extensive circumstantial evidence indicates that patients with a predicted severe attack of acute biliary pancreatitis (ABP) should undergo an endoscopic retrograde cholangiography with papillotomy (ERC/PT). However, in clinical practice this procedure is not always performed. This study was conducted to compare outcome in patients with and without ERC/PT. METHODOLOGY: Thirty-five of 80 patients admitted with ABP had a predicted severe attack (three or more Ranson criteria). Only in 24 of these 35 patients was an ERC/PT performed. RESULTS: In the ERC/PT group, significantly less pancreatic necrosis (8 vs. 64%, p <0.001) occurred, hospital stay was shorter (median 22 +/- 5 vs. 51 +/- 19 days, P=0.08) and mortality was lower (8 vs. 36%, P=0.01). Twenty-three patients (66%) underwent cholecystectomy after a median period of 10 weeks (range 0-26 weeks) after discharge. During the waiting period, in the ERC/PT group, two patients developed acute cholecystitis whereas recurrent ABP and common bile duct stones occurred in one patient each. CONCLUSIONS: In patients with a predicted severe attack of ABP, performing ERC/PT is associated with less morbidity and lower mortality

AB - BACKGROUND/AIMS: Extensive circumstantial evidence indicates that patients with a predicted severe attack of acute biliary pancreatitis (ABP) should undergo an endoscopic retrograde cholangiography with papillotomy (ERC/PT). However, in clinical practice this procedure is not always performed. This study was conducted to compare outcome in patients with and without ERC/PT. METHODOLOGY: Thirty-five of 80 patients admitted with ABP had a predicted severe attack (three or more Ranson criteria). Only in 24 of these 35 patients was an ERC/PT performed. RESULTS: In the ERC/PT group, significantly less pancreatic necrosis (8 vs. 64%, p <0.001) occurred, hospital stay was shorter (median 22 +/- 5 vs. 51 +/- 19 days, P=0.08) and mortality was lower (8 vs. 36%, P=0.01). Twenty-three patients (66%) underwent cholecystectomy after a median period of 10 weeks (range 0-26 weeks) after discharge. During the waiting period, in the ERC/PT group, two patients developed acute cholecystitis whereas recurrent ABP and common bile duct stones occurred in one patient each. CONCLUSIONS: In patients with a predicted severe attack of ABP, performing ERC/PT is associated with less morbidity and lower mortality

M3 - Article

C2 - 15782989

SN - 0172-6390

VL - 52

SP - 37

EP - 39

JO - Hepato-Gastroenterology

JF - Hepato-Gastroenterology

IS - 61

ER -