@article{cc633da7f2774add9c4cfa1bd2846284,
title = "Beyond multidrug-resistant tuberculosis in Europe: A TBNET study",
abstract = "{\textcopyright} 2015 The Union.The emergence of drug-resistant tuberculosis (TB) is a challenge to TB control in Europe.We evaluated secondline drug susceptibility testing in Mycobacterium tuberculosis isolates from patients with multidrugresistant, pre-extensively drug-resistant (pre-XDR-TB) and XDR-TB at 23 TBNET sites in 16 European countries. Over 30% of bacilli from patients with pre-XDR-TB showed resistance to any fluoroquinolone and almost 70% to any second-line injectable drug. Respectively >90% and >80% of the XDR-TB strains tested showed phenotypic resistance to pyrazinamide and ethambutol. Resistance to prothionamide/ethionamide was high in bacilli from pre-XDR-TB patients (43%) and XDR-TB patients (49%).",
author = "{for the TBNET} and G. G{\"u}nther and {Van Leth}, F. and N. Altet and M. Dedicoat and R. Duarte and G. Gualano and H. Kunst and I. Muylle and V. Spinu and S. Tiberi and P. Viiklepp and C. Lange and {AUTHOR GROUP} and S. Alexandru and I. Cernenco and A. Ciobanu and A. Donica and J. Cayla and L. Fina and Galvao, {M. L. de Souza} and J. Maldonado and K. Avsar and D. Bang and Andersen, {A. B.} and R. Barbuta and V. Dubceac and G. Bothamley and V. Crudu and M. Davilovits and A. Atunes and {de Lange}, W. and V. Leimane and L. Rusmane and {de Lorenzo}, S. and F. Cuppen and {de Guchtenaire}, I. and C. Magis-Escurra and A.-M. McLaughlin and R. Meesters and {te Pas}, M. and B. Prins and R. M{\"u}tterlein and J. Kotrbova and V. Polcov{\'a} and M. Vasakova and E. Pontali and R. Rumetshofer and M. Rowhani and A. Skrahina and V. Avchinko and D. Katovich",
year = "2015",
month = dec,
day = "1",
doi = "https://doi.org/10.5588/ijtld.15.0274",
language = "English",
volume = "19",
pages = "1524--1527",
journal = "International journal of tuberculosis and lung disease",
issn = "1027-3719",
publisher = "International Union against Tubercul. and Lung Dis.",
number = "12",
}