TY - JOUR
T1 - Biomarkers in Sepsis
AU - van Engelen, Tjitske S. R.
AU - Wiersinga, Willem Joost
AU - Scicluna, Brendon P.
AU - van der Poll, Tom
PY - 2018
Y1 - 2018
N2 - A biomarker is a characteristic by which a (patho) physiologic process can be identified. Biomarkers can be of diagnostic value (to discriminate infection from noninfectious conditions or to determine the causative pathogen), of prognostic value (to assign risk profiles and predict outcome), and in the future may be of theranostic value (to aid in the selection and monitoring of therapy). Systems biology provides a promising tool for the discovery of novel biomarkers. Biomarkers can be the key to personalized targeted treatment in the future clinical management of sepsis
AB - A biomarker is a characteristic by which a (patho) physiologic process can be identified. Biomarkers can be of diagnostic value (to discriminate infection from noninfectious conditions or to determine the causative pathogen), of prognostic value (to assign risk profiles and predict outcome), and in the future may be of theranostic value (to aid in the selection and monitoring of therapy). Systems biology provides a promising tool for the discovery of novel biomarkers. Biomarkers can be the key to personalized targeted treatment in the future clinical management of sepsis
U2 - https://doi.org/10.1016/j.ccc.2017.08.010
DO - https://doi.org/10.1016/j.ccc.2017.08.010
M3 - Article
C2 - 29149935
SN - 0749-0704
VL - 34
SP - 139-+
JO - Critical Care Clinics
JF - Critical Care Clinics
IS - 1
ER -