TY - JOUR
T1 - Body mass index is related to microvascular vasomotion, this is partly explained by adiponectin.
AU - de Boer, M.P.
AU - Wijnstok, N.J.
AU - Serne, E.H.
AU - Eringa, E.C.
AU - Stehouwer, C.D.A.
AU - Flyvbjerg, A.
AU - Hoekstra, T.
AU - Heijmans, M.W.
AU - Meijer, R.I.
AU - Twisk, J.
AU - Smulders, Y.
PY - 2014
Y1 - 2014
N2 - Objective: obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, so-called 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Alterations in vasomotion have been found using extreme body mass index (BMI) phenotypes. Whether these alterations can be translated to the general population is unknown. The aim was to retrospectively investigate relationships between BMI, vasomotion and adipokines in a population-based cohort. Methods: Adiposity, vasomotion, adiponectin and leptin were determined in 94 apparently healthy participants (age 42 years, 46 men, mean BMI 25·5 ± 3·8 kg/m
AB - Objective: obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, so-called 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Alterations in vasomotion have been found using extreme body mass index (BMI) phenotypes. Whether these alterations can be translated to the general population is unknown. The aim was to retrospectively investigate relationships between BMI, vasomotion and adipokines in a population-based cohort. Methods: Adiposity, vasomotion, adiponectin and leptin were determined in 94 apparently healthy participants (age 42 years, 46 men, mean BMI 25·5 ± 3·8 kg/m
U2 - https://doi.org/10.1111/eci.12284
DO - https://doi.org/10.1111/eci.12284
M3 - Article
C2 - 24854850
SN - 0014-2972
VL - 44
SP - 660
EP - 667
JO - European Journal of Clinical Investigation
JF - European Journal of Clinical Investigation
IS - 7
ER -
