Both R5 and X4 human immunodeficiency virus type 1 variants persist during prolonged therapy with five antiretroviral drugs

Ronald P. van Rij; Janny A. Visser; Rieneke M. E. van Praag; Ronald Rientsma; Jan M. Prins; Joep M. A. Lange; Hanneke Schuitemaker

doi:https://doi.org/10.1128/JVI.76.6.3054-3058.2002

Both R5 and X4 human immunodeficiency virus type 1 variants persist during prolonged therapy with five antiretroviral drugs

Ronald P. van Rij, Janny A. Visser, Rieneke M. E. van Praag, Ronald Rientsma, Jan M. Prins, Joep M. A. Lange, Hanneke Schuitemaker

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Abstract

A viral reservoir of human immunodeficiency virus type 1 (HIV-1)-infected, resting CD4(+) T cells persists despite suppression of plasma viremia by combination antiretroviral therapy. In a longitudinal analysis of three patients treated with a five-drug regimen, both R5 and X4 HIV-1 variants persisted in the cellular reservoir for up to 3 years

Original language	English
Pages (from-to)	3054-3058
Journal	Journal of Virology
Volume	76
Issue number	6
DOIs	https://doi.org/10.1128/JVI.76.6.3054-3058.2002
Publication status	Published - 2002

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https://doi.org/10.1128/JVI.76.6.3054-3058.2002

Cite this

@article{f88f0831696649768ebd285830619791,

title = "Both R5 and X4 human immunodeficiency virus type 1 variants persist during prolonged therapy with five antiretroviral drugs",

abstract = "A viral reservoir of human immunodeficiency virus type 1 (HIV-1)-infected, resting CD4(+) T cells persists despite suppression of plasma viremia by combination antiretroviral therapy. In a longitudinal analysis of three patients treated with a five-drug regimen, both R5 and X4 HIV-1 variants persisted in the cellular reservoir for up to 3 years",

author = "{van Rij}, {Ronald P.} and Visser, {Janny A.} and {van Praag}, {Rieneke M. E.} and Ronald Rientsma and Prins, {Jan M.} and Lange, {Joep M. A.} and Hanneke Schuitemaker",

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T1 - Both R5 and X4 human immunodeficiency virus type 1 variants persist during prolonged therapy with five antiretroviral drugs

AU - van Rij, Ronald P.

AU - Visser, Janny A.

AU - van Praag, Rieneke M. E.

AU - Rientsma, Ronald

AU - Prins, Jan M.

AU - Lange, Joep M. A.

AU - Schuitemaker, Hanneke

PY - 2002

Y1 - 2002

N2 - A viral reservoir of human immunodeficiency virus type 1 (HIV-1)-infected, resting CD4(+) T cells persists despite suppression of plasma viremia by combination antiretroviral therapy. In a longitudinal analysis of three patients treated with a five-drug regimen, both R5 and X4 HIV-1 variants persisted in the cellular reservoir for up to 3 years

AB - A viral reservoir of human immunodeficiency virus type 1 (HIV-1)-infected, resting CD4(+) T cells persists despite suppression of plasma viremia by combination antiretroviral therapy. In a longitudinal analysis of three patients treated with a five-drug regimen, both R5 and X4 HIV-1 variants persisted in the cellular reservoir for up to 3 years

U2 - https://doi.org/10.1128/JVI.76.6.3054-3058.2002

DO - https://doi.org/10.1128/JVI.76.6.3054-3058.2002

M3 - Article

C2 - 11861873

SN - 0022-538X

VL - 76

SP - 3054

EP - 3058

JO - Journal of Virology

JF - Journal of Virology

IS - 6

ER -