TY - JOUR
T1 - Brief Report on 3-Weekly Paclitaxel Carboplatin Efficacy in Locally Advanced or Metastatic Squamous Vulvar Cancer
AU - Amant, Frédéric
AU - Nooij, Linda
AU - Annibali, Daniela
AU - van Rompuy, Anne-Sophie
AU - Han, Sileny
AU - van den Bulck, Heidi
AU - Goffin, Frédéric
PY - 2018
Y1 - 2018
N2 - In this brief report, we present our experience with 3-weekly paclitaxel-carboplatin chemotherapy for patients with vulvar cancer. Two patients with locally advanced disease had an impressive response allowing standard vulvar cancer surgery. One patient with metastatic disease had local stable disease though it was progressive in the lymph nodes. The available literature is sparse and retrospective. Based on promising results, however, a prospective multicenter study is mandatory in order to obtain full data in a larger series of patients in order to learn the benefits of neoadjuvant paclitaxel-carboplatin and compare the results with chemoradiation.
AB - In this brief report, we present our experience with 3-weekly paclitaxel-carboplatin chemotherapy for patients with vulvar cancer. Two patients with locally advanced disease had an impressive response allowing standard vulvar cancer surgery. One patient with metastatic disease had local stable disease though it was progressive in the lymph nodes. The available literature is sparse and retrospective. Based on promising results, however, a prospective multicenter study is mandatory in order to obtain full data in a larger series of patients in order to learn the benefits of neoadjuvant paclitaxel-carboplatin and compare the results with chemoradiation.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053800071&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30227411
U2 - https://doi.org/10.1159/000487435
DO - https://doi.org/10.1159/000487435
M3 - Article
C2 - 30227411
SN - 0378-7346
VL - 83
SP - 620
EP - 626
JO - Gynecologic and Obstetric Investigation
JF - Gynecologic and Obstetric Investigation
IS - 6
ER -