Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma

Robin Cornelissen, Suresh Senan, Imogeen E. Antonisse, Hauw Liem, Youke K Y Tan, Arjan Rudolphus, Joachim G J V Aerts

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)


Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans organizing pneumonia (BOOP). We report on two patients with carcinoma of the breast who developed an interstitial lung disease consistent with BOOP. BOOP responds to treatment with corticosteroids and the prognosis is generally good despite of the need for long-term administration of corticosteroids as relapses can occur during tapering of steroids. This report provides guidelines for the evaluation and treatment of patients with pulmonary infiltrates after radiotherapy.

Original languageEnglish
Article number2
JournalRadiation Oncology
Issue number1
Publication statusPublished - 3 Jan 2007

Cite this