C-reactive protein kinetics and its predictive value in orthopedic (trauma) surgery: A systematic review

J. Kruidenier; S. A. Dingemans; S. Van Dieren; V. M. De Jong; J. C. Goslings; T. Schepers

C-reactive protein kinetics and its predictive value in orthopedic (trauma) surgery: A systematic review

J. Kruidenier, S. A. Dingemans, S. Van Dieren, V. M. De Jong, J. C. Goslings, T. Schepers

Surgery (AMC)

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

In Orthopedic Trauma Surgery (OTS), C-reactive-protein (CRP) is a widely used marker for the diagnosis of postoperative wound infections (POWI's) and other complications. The aim of this systematic review was to describe specific CRP kinetics and to evaluate the diagnostic value of CRP for te detection of post-operative complications in OTS. The same pattern is reported consistently, where the highest levels of CRP are found at post-operative-day two or three, returning to normal in three weeks. Amplitude varies per procedure. Persistently high CRP levels or secondary increases may indicate complications. A low CRP may be used to rule out complications.

Original language	English
Pages (from-to)	397-406
Number of pages	10
Journal	Acta orthopaedica Belgica
Volume	84
Issue number	4
Publication status	Published - 1 Dec 2018

Keywords

C-reactive protein
Diagnostic tool
Orthopedic surgery
Surgical site infection

Cite this

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abstract = "In Orthopedic Trauma Surgery (OTS), C-reactive-protein (CRP) is a widely used marker for the diagnosis of postoperative wound infections (POWI's) and other complications. The aim of this systematic review was to describe specific CRP kinetics and to evaluate the diagnostic value of CRP for te detection of post-operative complications in OTS. The same pattern is reported consistently, where the highest levels of CRP are found at post-operative-day two or three, returning to normal in three weeks. Amplitude varies per procedure. Persistently high CRP levels or secondary increases may indicate complications. A low CRP may be used to rule out complications.",

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T2 - A systematic review

AU - Kruidenier, J.

AU - Dingemans, S. A.

AU - Van Dieren, S.

AU - De Jong, V. M.

AU - Goslings, J. C.

AU - Schepers, T.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - In Orthopedic Trauma Surgery (OTS), C-reactive-protein (CRP) is a widely used marker for the diagnosis of postoperative wound infections (POWI's) and other complications. The aim of this systematic review was to describe specific CRP kinetics and to evaluate the diagnostic value of CRP for te detection of post-operative complications in OTS. The same pattern is reported consistently, where the highest levels of CRP are found at post-operative-day two or three, returning to normal in three weeks. Amplitude varies per procedure. Persistently high CRP levels or secondary increases may indicate complications. A low CRP may be used to rule out complications.

AB - In Orthopedic Trauma Surgery (OTS), C-reactive-protein (CRP) is a widely used marker for the diagnosis of postoperative wound infections (POWI's) and other complications. The aim of this systematic review was to describe specific CRP kinetics and to evaluate the diagnostic value of CRP for te detection of post-operative complications in OTS. The same pattern is reported consistently, where the highest levels of CRP are found at post-operative-day two or three, returning to normal in three weeks. Amplitude varies per procedure. Persistently high CRP levels or secondary increases may indicate complications. A low CRP may be used to rule out complications.

KW - C-reactive protein

KW - Diagnostic tool

KW - Orthopedic surgery

KW - Surgical site infection

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SN - 0001-6462

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JO - Acta orthopaedica Belgica

JF - Acta orthopaedica Belgica

IS - 4

ER -

C-reactive protein kinetics and its predictive value in orthopedic (trauma) surgery: A systematic review

Abstract

Keywords

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