TY - JOUR
T1 - Cardiovascular risk in adults with Delayed Sleep Phase Syndrome (DSPS) and Attention-Deficit/Hyperactivity Disorder (ADHD)
AU - van Andel, Emma
AU - Bijlenga, Denise
AU - Vogel, Suzan W.N.
AU - Beekman, Aartjan T.F.
AU - Kooij, J. J.Sandra
N1 - Funding Information: This work was supported by an unrestricted grant from research fund Fonds NutsOhra under Grant FNO #1102-026. We thank all participants for their time and effort, our team at PsyQ Program Adult ADHD for their help with inclusion, Star-shl in Rotterdam for the use of their ABPM and ECG recording materials, and Fysiologic for HRV analysis. Publisher Copyright: © 2023 Taylor & Francis Group, LLC.
PY - 2023
Y1 - 2023
N2 - Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with a wide variety of sleep problems. The most common sleep disturbance in adults with ADHD is Delayed Sleep Phase Syndrome (DSPS), which leads to sleep insufficiency and social jetlag. ADHD, short sleep, and social jetlag have independently been associated with poorer cardiovascular health. Adults with both DSPS and ADHD may be particularly at risk of developing cardiovascular diseases (CVDs), which are the leading cause of death worldwide. In this study, 24-hour resting-state heart rate variability (HRV) was measured as a biomarker for cardiovascular health in 49 adults (18-55y) with DSPS and ADHD. The prevalence of cardiovascular risk factors obesity, smoking, and hypertension was determined. The majority of participants scored within average ranges for all HRV measures. The prevalence of obesity was normal compared to the general population. Smoking and hypertension were more prevalent, but not related to HRV. In conclusion, we found no evidence for a high risk of CVDs in this group. It however remains important to study cardiovascular risk in adults with DSPS and ADHD using different methodologies. Trial Registration: FASE, https://www.trialregister.nl/, #NTR3831.
AB - Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with a wide variety of sleep problems. The most common sleep disturbance in adults with ADHD is Delayed Sleep Phase Syndrome (DSPS), which leads to sleep insufficiency and social jetlag. ADHD, short sleep, and social jetlag have independently been associated with poorer cardiovascular health. Adults with both DSPS and ADHD may be particularly at risk of developing cardiovascular diseases (CVDs), which are the leading cause of death worldwide. In this study, 24-hour resting-state heart rate variability (HRV) was measured as a biomarker for cardiovascular health in 49 adults (18-55y) with DSPS and ADHD. The prevalence of cardiovascular risk factors obesity, smoking, and hypertension was determined. The majority of participants scored within average ranges for all HRV measures. The prevalence of obesity was normal compared to the general population. Smoking and hypertension were more prevalent, but not related to HRV. In conclusion, we found no evidence for a high risk of CVDs in this group. It however remains important to study cardiovascular risk in adults with DSPS and ADHD using different methodologies. Trial Registration: FASE, https://www.trialregister.nl/, #NTR3831.
KW - Attention-deficit/hyperactivity disorder
KW - cardiovascular health
KW - cardiovascular risk
KW - delayed sleep phase syndrome
KW - heart rate variability
UR - http://www.scopus.com/inward/record.url?scp=85178249737&partnerID=8YFLogxK
U2 - https://doi.org/10.1080/07420528.2023.2287058
DO - https://doi.org/10.1080/07420528.2023.2287058
M3 - Article
C2 - 38017699
SN - 0742-0528
VL - 40
SP - 1566
EP - 1573
JO - Chronobiology International
JF - Chronobiology International
IS - 12
ER -