TY - JOUR
T1 - Case-Control Studies - An Efficient Observational Study Design
AU - van Stralen, Karlijn J.
AU - Dekker, Friedo W.
AU - Zoccali, Carmine
AU - Jager, Kitty J.
PY - 2010
Y1 - 2010
N2 - Case-control studies are an efficient research method for investigating risk factors of a disease. The method involves the comparison of the odds of exposure in a patient group with that of the odds of exposure in a control group. As only a minority of the population is included in the study, less time can be devoted to those who remain free of the disease of interest. The design of a case-control study can be complex due to the selection of the appropriate cases and controls. Cases can be identified in a prospective and retrospective manner from various sources. Controls can be obtained via the patient, random digit dialing or in a hospital and all at different points in the time period of the study. All options have their own advantages and disadvantages. Furthermore, different forms of bias, such as recall bias and selection bias, can occur. When appropriately designed, case-control studies can provide the same information as in a cohort study, in a more rapid and efficient manner
AB - Case-control studies are an efficient research method for investigating risk factors of a disease. The method involves the comparison of the odds of exposure in a patient group with that of the odds of exposure in a control group. As only a minority of the population is included in the study, less time can be devoted to those who remain free of the disease of interest. The design of a case-control study can be complex due to the selection of the appropriate cases and controls. Cases can be identified in a prospective and retrospective manner from various sources. Controls can be obtained via the patient, random digit dialing or in a hospital and all at different points in the time period of the study. All options have their own advantages and disadvantages. Furthermore, different forms of bias, such as recall bias and selection bias, can occur. When appropriately designed, case-control studies can provide the same information as in a cohort study, in a more rapid and efficient manner
U2 - https://doi.org/10.1159/000242442
DO - https://doi.org/10.1159/000242442
M3 - Article
C2 - 19797931
SN - 1660-2110
VL - 114
SP - c1-c4
JO - Nephron. Clinical practice
JF - Nephron. Clinical practice
IS - 1
ER -