TY - JOUR
T1 - Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature
AU - Leroy, Jordan
AU - Cornu, Marjorie
AU - Deleplancque, Anne-Sophie
AU - Bart, Aldert
AU - Loridant, S. verine
AU - Fréalle, Emilie
AU - Dutoit, Emmanuel
AU - Gaillot, Olivier
AU - van Gool, Tom
AU - Puisieux, François
AU - Labalette, Pierre
AU - Sendid, Boualem
PY - 2018
Y1 - 2018
N2 - Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. In our patient, Weber trichrome staining of conjunctival scrapings revealed rounded elements approximately 1-3 μm in size. Conventional polymerase chain reaction analysis by ribosomal RNA subunit sequencing showed 100% identity with Vittaforma corneae. Treatment by corneal debridement combined with fluoroquinolone eye drops allowed complete resolution of the lesions. Although rare, ocular microsporidiosis should be investigated in a patient who is native to Asia or has returned from an endemic area and presents with keratoconjunctivitis of undetermined etiology.
AB - Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. In our patient, Weber trichrome staining of conjunctival scrapings revealed rounded elements approximately 1-3 μm in size. Conventional polymerase chain reaction analysis by ribosomal RNA subunit sequencing showed 100% identity with Vittaforma corneae. Treatment by corneal debridement combined with fluoroquinolone eye drops allowed complete resolution of the lesions. Although rare, ocular microsporidiosis should be investigated in a patient who is native to Asia or has returned from an endemic area and presents with keratoconjunctivitis of undetermined etiology.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85049609274&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/29692301
U2 - https://doi.org/10.4269/ajtmh.18-0015
DO - https://doi.org/10.4269/ajtmh.18-0015
M3 - Review article
C2 - 29692301
SN - 0002-9637
VL - 99
SP - 90
EP - 93
JO - American journal of tropical medicine and hygiene
JF - American journal of tropical medicine and hygiene
IS - 1
ER -