Case series of four secondary mucormycosis infections in COVID-19 patients, the Netherlands, December 2020 to May 2021

Jochem B. Buil, Arthur R. H. van Zanten, Robbert G. Bentvelsen, Tom A. Rijpstra, Bram Goorhuis, Sanne van der Voort, Linda J. Wammes, Jeroen A. Janson, Max Melchers, Moniek Heusinkveld, Willem J. G. Melchers, Ed J. Kuijper, Paul E. Verweij

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Abstract

We describe four secondary fungal infections caused by Mucorales species in COVID-19 patients. Three COVID-19 associated mucormycosis (CAM) occurred in ICU, one outside ICU. All were men aged > 50 years, three died. Clinical presentations included pulmonary, rhino-orbital cerebral and disseminated infection. Infections occurred in patients with and without diabetes mellitus. CAM is an emerging disease and our observations underscore the need to be aware of invasive mucormycosis, including in COVID-19 patients without (poorly controlled) diabetes mellitus and outside ICU.
Original languageEnglish
Article number2100510
JournalEuro surveillance
Volume26
Issue number23
DOIs
Publication statusPublished - 10 Jun 2021

Keywords

  • COVID-19
  • invasive mucormycosis

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