TY - JOUR
T1 - Central but not peripheral fat mass percentage is associated with blood pressure components in the elderly
AU - van Dijk, Suzanne
AU - van den Meiracker, Anton
AU - van der Cammen, Tischa
AU - Mattace Raso, Francesco
AU - van der Velde, Nathalie
PY - 2012
Y1 - 2012
N2 - Methods: cross-sectional design. Using dual-energy X-ray absorptiometry (DEXA), fat mass was measured within a geriatric outpatient clinic population. Blood pressure was measured with an oscillometric device, and aortic blood pressure and augmentation index (AIx) were obtained by radial artery tonometry, using the SphygmoCor system. Multivariate adjustment for confounders was performed using linear regression analyses. Results: totally, 216 subjects were included (age 77.3 years +/- 6.1, 34.7% male). The truncal fat mass percentage, but not the peripheral fat mass percentage, was positively associated with the peripheral systolic blood pressure (SBP) [beta 0.07 (95% CI: 0.02 to 0.11)] and the peripheral pulse pressure (PP) [beta 0.07 (95% CI: 0.02 to 0.11)], but negatively with the peripheral diastolic blood pressure (DBP) [beta -0.16 (95% CI -0.27 to -0.04)]. The truncal fat mass percentage was similarly associated with estimated aortic blood pressure components, but no association was found between the truncal fat mass percentage and the AIx. Conclusion: in older persons, the truncal fat mass percentage as a reflection of the central fat mass percentage, but not the peripheral fat mass percentage is associated with peripheral and aortic blood pressure components
AB - Methods: cross-sectional design. Using dual-energy X-ray absorptiometry (DEXA), fat mass was measured within a geriatric outpatient clinic population. Blood pressure was measured with an oscillometric device, and aortic blood pressure and augmentation index (AIx) were obtained by radial artery tonometry, using the SphygmoCor system. Multivariate adjustment for confounders was performed using linear regression analyses. Results: totally, 216 subjects were included (age 77.3 years +/- 6.1, 34.7% male). The truncal fat mass percentage, but not the peripheral fat mass percentage, was positively associated with the peripheral systolic blood pressure (SBP) [beta 0.07 (95% CI: 0.02 to 0.11)] and the peripheral pulse pressure (PP) [beta 0.07 (95% CI: 0.02 to 0.11)], but negatively with the peripheral diastolic blood pressure (DBP) [beta -0.16 (95% CI -0.27 to -0.04)]. The truncal fat mass percentage was similarly associated with estimated aortic blood pressure components, but no association was found between the truncal fat mass percentage and the AIx. Conclusion: in older persons, the truncal fat mass percentage as a reflection of the central fat mass percentage, but not the peripheral fat mass percentage is associated with peripheral and aortic blood pressure components
U2 - https://doi.org/10.1093/ageing/afs056
DO - https://doi.org/10.1093/ageing/afs056
M3 - Article
C2 - 22555340
SN - 0002-0729
VL - 41
SP - 534
EP - 540
JO - Age and ageing
JF - Age and ageing
IS - 4
ER -