TY - JOUR
T1 - Characteristics of clinical Helicobacter pylori strains from Ecuador.
AU - Debets-Ossenkopp, Y.J.
AU - Reyes, G
AU - Mulder, J.
AU - aan de Stegge, BM
AU - Peters, JT
AU - Savelkoul, P.H.M.
AU - Tanca, J
AU - Pena, A.S.
AU - Vandenbroucke-Grauls, C.M.J.E.
AU - aan de Stegge, Birgit M.
AU - Peters, José T. A. M.
PY - 2003
Y1 - 2003
N2 - In Ecuador, Helicobacter pylori infections are highly prevalent. A total of 42 H. pylori clinical isolates from 86 patients attending the outpatient clinic of the gastroenterology department of the university hospital of Guayaquil in Ecuador were characterized. Their susceptibility, and cagA and vacA status were determined. Resistance to metronidazole and clarithromycin was found in 80.9% and 9.5% of strains, respectively. Neither amoxicillin- nor tetracycline-resistant strains were found. The most prevalent genotype was the cagA(+), vacA s1b,m1 type. This genotype was associated with gastric cancer and peptic ulcer. Typing by random amplified polymorphic DNA showed no genetic relationship among the strains
AB - In Ecuador, Helicobacter pylori infections are highly prevalent. A total of 42 H. pylori clinical isolates from 86 patients attending the outpatient clinic of the gastroenterology department of the university hospital of Guayaquil in Ecuador were characterized. Their susceptibility, and cagA and vacA status were determined. Resistance to metronidazole and clarithromycin was found in 80.9% and 9.5% of strains, respectively. Neither amoxicillin- nor tetracycline-resistant strains were found. The most prevalent genotype was the cagA(+), vacA s1b,m1 type. This genotype was associated with gastric cancer and peptic ulcer. Typing by random amplified polymorphic DNA showed no genetic relationship among the strains
U2 - https://doi.org/10.1093/jac/dkg023
DO - https://doi.org/10.1093/jac/dkg023
M3 - Article
C2 - 12493799
SN - 0305-7453
VL - 51
SP - 141
EP - 145
JO - Journal of antimicrobial chemotherapy
JF - Journal of antimicrobial chemotherapy
IS - 1
ER -