CHECK (Cohort Hip and Cohort Knee): similarities and differences with the Osteoarthritis Initiative

J. Wesseling, J. Dekker, W.D.J. van de Berg, S.M. Bierma-Zeinstra, M. Boers, H.A. Cats, P. Deckers, K.A. Gorter, P.H.T.G. Heuts, W.K.H.A. Hilberdink, M. Kloppenburg, R.G. Nelissen, F.G.J. Oosterveld, J.C.M. Oostveen, L.D. Roorda, M. Viergever, S. ten Wolde, F.P.J.G. Lafeber, J.W.J. Bijlsma, W. B. van den BergK. J. Gorter

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Objective: To describe the osteoarthritis study population of CHECK (Cohort Hip and Cohort Knee) in comparison with relevant selections of the study population of the Osteoarthritis Initiative (OAI) based on clinical status and radiographic parameters. Methods: In The Netherlands a prospective 10-year follow-up study was initiated by the Dutch Arthritis Association on participants with early osteoarthritis-related complaints of hip and/or knee: CHECK. In parallel in the USA an observational 4-year follow-up study, the OAI, was started by the National Institutes of Health, on patients with or at risk of symptomatic knee osteoarthritis. For comparison with CHECK, the entire cohort and a subgroup of individuals excluding those with exclusively hip pain were compared with relevant subpopulations of the OAI. Results: At baseline, CHECK included 1002 participants with in general similar characteristics as described for the OAI. However, significantly fewer individuals in CHECK had radiographic knee osteoarthritis at baseline when compared with the OAI (p
Original languageEnglish
Pages (from-to)1413-1419
Number of pages7
JournalAnnals of the rheumatic diseases
Issue number9
Publication statusPublished - 2009

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