TY - JOUR
T1 - Childhood Brain Tumor Survivors at Risk for Impaired Health-related Quality of Life
AU - Aukema, Eline J.
AU - Schouten-van Meeteren, A. Y. Netteke
AU - Last, Bob F.
AU - Maurice-Stam, Heleen
AU - Grootenhuis, Martha A.
PY - 2013
Y1 - 2013
N2 - This study aimed to assess health-related quality of life (HRQOL)-mean scores and percentages at risk for impaired HRQOL in childhood brain tumor survivors (CBTS) and to explore differences between CBTS treated with surgery only (SO) versus CBTS treated with surgery and adjuvant therapy (SA). HRQOL was evaluated in 34 CBTS (mean age=14.7 y; mean time since the end of treatment=6.4 y) with the KIDSCREEN. Being at risk for impaired HRQOL was defined as a T-score 1 SD below the norm population mean. The total and the SA group, but not the SO group, had significantly lower mean scores than the Dutch norm population in the domains of physical well-being, psychological well-being, and peers and social support. High percentages (35% to 53%) of both the SO and the SA groups appeared to be at risk for impaired HRQOL in the domains of physical well-being, moods and emotions, peers and social support, and bullying, compared to 16% in the norm population. In conclusion, although HRQOL in some domains appeared similar to the norm population, a considerable number of CBTS-reported impaired HRQOL in several other domains. It is recommended to systematically monitor HRQOL in CBTS regardless of the therapy applied
AB - This study aimed to assess health-related quality of life (HRQOL)-mean scores and percentages at risk for impaired HRQOL in childhood brain tumor survivors (CBTS) and to explore differences between CBTS treated with surgery only (SO) versus CBTS treated with surgery and adjuvant therapy (SA). HRQOL was evaluated in 34 CBTS (mean age=14.7 y; mean time since the end of treatment=6.4 y) with the KIDSCREEN. Being at risk for impaired HRQOL was defined as a T-score 1 SD below the norm population mean. The total and the SA group, but not the SO group, had significantly lower mean scores than the Dutch norm population in the domains of physical well-being, psychological well-being, and peers and social support. High percentages (35% to 53%) of both the SO and the SA groups appeared to be at risk for impaired HRQOL in the domains of physical well-being, moods and emotions, peers and social support, and bullying, compared to 16% in the norm population. In conclusion, although HRQOL in some domains appeared similar to the norm population, a considerable number of CBTS-reported impaired HRQOL in several other domains. It is recommended to systematically monitor HRQOL in CBTS regardless of the therapy applied
U2 - https://doi.org/10.1097/MPH.0b013e31829b7ec6
DO - https://doi.org/10.1097/MPH.0b013e31829b7ec6
M3 - Article
C2 - 24152587
SN - 1077-4114
VL - 35
SP - 603
EP - 609
JO - Journal of pediatric hematology/oncology
JF - Journal of pediatric hematology/oncology
IS - 8
ER -