TY - JOUR
T1 - Circadian rhythms in white adipose tissue
AU - van der Spek, Rianne
AU - Kreier, Felix
AU - Fliers, Eric
AU - Kalsbeek, Andries
PY - 2012
Y1 - 2012
N2 - Adipose tissue is an important endocrine organ. It is involved in the regulation of energy metabolism by secreting factors (adipokines) that regulate appetite, food intake, glucose disposal, and energy expenditure. Many of these adipokines display profound day/ night rhythms, and accumulating evidence links disruption of these rhythms to metabolic diseases such as obesity and type 2 diabetes. Here, we briefly present the circadian system, describe the development of white adipose tissue (WAT) and its depot-specific characteristics and innervation, we discuss energy storage in WAT and, lastly, review recent findings that link circadian rhythmicity to adipose tissue biology and obesity
AB - Adipose tissue is an important endocrine organ. It is involved in the regulation of energy metabolism by secreting factors (adipokines) that regulate appetite, food intake, glucose disposal, and energy expenditure. Many of these adipokines display profound day/ night rhythms, and accumulating evidence links disruption of these rhythms to metabolic diseases such as obesity and type 2 diabetes. Here, we briefly present the circadian system, describe the development of white adipose tissue (WAT) and its depot-specific characteristics and innervation, we discuss energy storage in WAT and, lastly, review recent findings that link circadian rhythmicity to adipose tissue biology and obesity
U2 - https://doi.org/10.1016/B978-0-444-59427-3.00011-3
DO - https://doi.org/10.1016/B978-0-444-59427-3.00011-3
M3 - Review article
C2 - 22877666
SN - 0079-6123
VL - 199
SP - 183
EP - 201
JO - Progress in brain research
JF - Progress in brain research
ER -