Clearance of cervical human papillomavirus infection by treatment for cervical dysplasia

L. J. Bollen, S. P. Tjong-A-Hung, J. van der Velden, B. W. Mol, K. Boer, F. J. ten Kate, O. P. Bleker, J. ter Schegget

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Abstract

OBJECTIVES: The aim of this study was to investigate the prevalence of human papillomavirus (HPV) after treatment for cervical dysplasia. STUDY DESIGN: The presence of HPV was investigated in cervical scrapes of 91 patients, before and after treatment, using consensus primers in the polymerase chain reaction. RESULTS: Before treatment for cervical dysplasia, 89 of 91 patients (98%) were HPV-positive compared with 28 of 91 patients (31%) after treatment. The HPV type present before treatment was found in the scrapes of only 9 of 89 patients (10%). Detection of HPV after treatment was associated with human immunodeficiency virus infection and incomplete conization. CONCLUSION: The HPV type present before treatment was frequently cleared by treatment for cervical dysplasia
Original languageEnglish
Pages (from-to)456-460
JournalSexually transmitted diseases
Volume24
Issue number8
DOIs
Publication statusPublished - 1997

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