Clinical aspects of non-severe hemophilia: Focus on bleeding, joint and treatment outcomes: Focus on bleeding, joint and treatment outcomes

S.C. Gouw, F.R. Kloosterman

Research output: PhD ThesisPhd-Thesis - Research and graduation internal

Abstract

Hemophilia A and B are rare inherited bleeding disorders, caused by mutations in the F8 or F9 gene on the X-chromosome leading to a deficiency of coagulation factor VIII (FVIII) or coagulation factor IX (FIX), respectively. As a result, persons with decreased coagulation FVIII/IX levels have an increased bleeding tendency. Classification of disease severity is based on the endogenous FVIII/IX
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • University of Amsterdam
Supervisors/Advisors
  • Fijnvandraat, Karin, Supervisor
  • Gouw, Samantha, Co-supervisor
  • Coppens, Michiel, Co-supervisor
  • Fijnvandraat, C.J., Supervisor, External person
Award date25 May 2023
Print ISBNs9789464830507
Publication statusPublished - 25 May 2023

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