TY - JOUR
T1 - Clinical Course of Nodular Regenerative Hyperplasia in Thiopurine Treated Inflammatory Bowel Disease Patients
AU - Dutch Initiative on Crohn and Colitis (ICC)
AU - Simsek, Melek
AU - Meijer, Berrie
AU - Ramsoekh, Dewkoemar
AU - Bouma, Gerd
AU - van der Wouden, Egbert-Jan
AU - den Hartog, Bert
AU - de Vries, Annemarie C.
AU - Hoentjen, Frank
AU - Dijkstra, Gerard
AU - de Boer, Sybrand Y.
AU - Jansen, Jeroen M.
AU - van der Meulen, Andrea E.
AU - Beukers, Ruud
AU - Brink, Menno A.
AU - Steinhauser, Toos
AU - Oldenburg, Bas
AU - Gilissen, Lennard P.
AU - Naber, Ton H.
AU - Verhagen, Marc A.
AU - de Boer, Nanne K. H.
AU - Mulder, Chris J. J.
PY - 2019/2/1
Y1 - 2019/2/1
N2 - Nodular regenerative hyperplasia (NRH) is a poorly understood liver condition, which is increasingly recognized in thiopurine-treated patients with inflammatory bowel disease (IBD).1 It is difficult to establish an optimal approach to NRH patients, because its manifestations are highly variable (from asymptomatic to symptoms of noncirrhotic portal hypertension [NCPH]) and the prognosis is unknown.2 The aim of this study was to identify NRH cases in IBD patients treated with azathioprine, mercaptopurine, and/or thioguanine, and to describe its clinical course.
AB - Nodular regenerative hyperplasia (NRH) is a poorly understood liver condition, which is increasingly recognized in thiopurine-treated patients with inflammatory bowel disease (IBD).1 It is difficult to establish an optimal approach to NRH patients, because its manifestations are highly variable (from asymptomatic to symptoms of noncirrhotic portal hypertension [NCPH]) and the prognosis is unknown.2 The aim of this study was to identify NRH cases in IBD patients treated with azathioprine, mercaptopurine, and/or thioguanine, and to describe its clinical course.
UR - http://www.scopus.com/inward/record.url?scp=85049621594&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.cgh.2018.05.009
DO - https://doi.org/10.1016/j.cgh.2018.05.009
M3 - Short survey
C2 - 29775790
SN - 1542-3565
VL - 17
SP - 568
EP - 570
JO - Clinical Gastroenterology and Hepatology
JF - Clinical Gastroenterology and Hepatology
IS - 3
ER -