Clinical Interventions to Prevent Preterm Birth in Multiple Pregnancies

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

Twin, triplet or higher order pregnancies are referred to as multiple pregnancies. The prevalence of multiple pregnancies is around 1 per 80 live births [1]. Twins can be either dizygotic, resulting from the fertilization of two separate ova during a single ovulatory cycle, or monozygotic, resulting from a single fertilized ovum that subsequently divides into two separate individuals. Dizygotic twins are more prevalent than monozygotic twins. Higher order multiples can result from either or both processes. Monozygotic twins can either be dichorionic (1/3), monochorionic (2/3), or mono-amniotic (1/3). Which type of monozygotic twin eventually develops depends on the moment of splitting of the fertilized ovum. If the ovum splits within the first 3 days dichorionic twins develop, if the ovum splits between 4 and 8 days monochorionic/diamniotic twins develop, between 8 and 12 days mono-amniotic twins develop, and if the ovum splits after 12 days this gives rise to conjoined twins.
Original languageEnglish
Title of host publicationFetal Therapy: Scientific Basis and Critical Appraisal of Clinical Benefits
PublisherCambridge University Press
Pages325-332
ISBN (Electronic)9781108564434
ISBN (Print)9781108474061
DOIs
Publication statusPublished - 1 Jan 2019

Publication series

NameFetal Therapy: Scientific Basis and Critical Appraisal of Clinical Benefits

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