TY - CHAP
T1 - Cobalt-Chromium everolimus-eluting stents
AU - Thondapu, Vikas
AU - Onuma, Yoshinobu
AU - Claessen, Bimmer E. P. M.
AU - Serruys, Patrick W.
AU - Barlis, Peter
PY - 2016/11/21
Y1 - 2016/11/21
N2 - Cobalt-chromium (CoCr) stents were largely born out of the need for a new generation of coronary stents preserving or improving the safety, efficacy, and deliverability of earlier iterations. This chapter provides an overview of several material and chemical properties of CoCr alloys that contribute to these stents’ superior biomechanics and biocompatibility. It discusses the technical description of the CoCr- everolimus-eluting stents (EES) and the clinical trials evaluating their safety and efficacy. The three overarching elements in the design of traditional drug-eluting stents (DES) are platform, polymer, and drug. The CoCr-EES are conscribed by the Xience V, Prime, Xpedition, and Alpine. A multitude of trials have proven the short- and long-term safety and efficacy of the CoCr-EES compared to first generation DES, and now these stents are considered the standard comparator for newer devices and scaffolds. The performance of the CoCr-EES in in-stent restenosis lesions (ISR) was evaluated in the Xience V USA prospective multicenter registry.
AB - Cobalt-chromium (CoCr) stents were largely born out of the need for a new generation of coronary stents preserving or improving the safety, efficacy, and deliverability of earlier iterations. This chapter provides an overview of several material and chemical properties of CoCr alloys that contribute to these stents’ superior biomechanics and biocompatibility. It discusses the technical description of the CoCr- everolimus-eluting stents (EES) and the clinical trials evaluating their safety and efficacy. The three overarching elements in the design of traditional drug-eluting stents (DES) are platform, polymer, and drug. The CoCr-EES are conscribed by the Xience V, Prime, Xpedition, and Alpine. A multitude of trials have proven the short- and long-term safety and efficacy of the CoCr-EES compared to first generation DES, and now these stents are considered the standard comparator for newer devices and scaffolds. The performance of the CoCr-EES in in-stent restenosis lesions (ISR) was evaluated in the Xience V USA prospective multicenter registry.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104482428&origin=inward
U2 - https://doi.org/10.1002/9781118983652.ch32
DO - https://doi.org/10.1002/9781118983652.ch32
M3 - Chapter
SN - 9781118976036
T3 - Interventional Cardiology: Principles and Practice
SP - 313
EP - 325
BT - Interventional Cardiology: Principles and Practice
A2 - Dangas, George D.
A2 - Di Mario, Carlo
A2 - Kipshidze, Nicholas N.
A2 - Barlis, Peter
A2 - Addo, Tayo
PB - Wiley
ER -