Cognitive functioning in elderly patients with early onset bipolar disorder

S. N.T.M. Schouws, J. B. Zoeteman, H. C. Comijs, M. L. Stek, A. T.F. Beekman

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28 Citations (Scopus)


Background: Very little is known about the long term cognitive sequelae of bipolar disorder. Aim: To investigate neuropsychological functioning in older euthymic persons with early onset bipolar disorder. Method: Fifteen older patients (age >60) with an early onset (<50 years) bipolar-I disorder in a euthymic mood were tested using a comprehensive neuropsychological test battery. Neuropsychological functioning was compared with that of a sex, age and education-matched group of 15 comparison subjects without mood disorders or memory complaints. Results: Bipolar subjects scored lower than comparison subjects on selective attention, verbal memory, verbal fluency and mental effort tests. Conclusions: The findings suggest that euthymic bipolar patients are impaired across a range of cognitive domains. This could represent a trait-like cognitive disability related to the disease, as the impairments are comparable with those found in younger bipolar patients.

Original languageEnglish
Pages (from-to)856-861
Number of pages6
JournalInternational journal of geriatric psychiatry
Issue number9
Publication statusPublished - Sept 2007


  • Bipolar disorder
  • Cognition
  • Elderly

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