Cognitive mediation of panic reduction during an early intervention for panic

P. Meulenbeek; P. Spinhoven; H.F.E. Smit; A.J.L.M. van Balkom; P. Cuijpers

doi:https://doi.org/10.1111/j.1600-0447.2009.01530.x

Cognitive mediation of panic reduction during an early intervention for panic

P. Meulenbeek, P. Spinhoven, H.F.E. Smit, A.J.L.M. van Balkom, P. Cuijpers

Psychiatry (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

Abstract

Objective: This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.

Method: We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD.

Results: First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant.

Conclusion: The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.

Original language	English
Pages (from-to)	20-29
Journal	Acta psychiatrica Scandinavica
Volume	122
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0447.2009.01530.x
Publication status	Published - 2010

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Cite this

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abstract = "Objective: This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.Method: We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD.Results: First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant.Conclusion: The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.",

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AU - Cuijpers, P.

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